Gastrin hexapeptide

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MedKoo CAT#: 597715

CAS#: 20994-88-1

Description: Gastrin hexapeptide is a hexapeptide from porcine antral mucosa.

Price and Availability

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Pricing updated 2020-03-29. Prices are subject to change without notice.

Gastrin hexapeptide is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 597715
Name: Gastrin hexapeptide
CAS#: 20994-88-1
Chemical Formula: C40H48N8O9S
Exact Mass: 816.3265
Molecular Weight: 816.93
Elemental Analysis: C, 58.81; H, 5.92; N, 13.72; O, 17.63; S, 3.92

Synonym: Gastrin hexapeptide; Tyr-gly-trp-met-asp-phe-NH2; Gastrin C-terminal hexapeptide;

IUPAC/Chemical Name: (3S,6S,9S,15S)-9-((1H-indol-3-yl)methyl)-15-amino-3-(((S)-1-amino-1-oxo-3-phenylpropan-2-yl)carbamoyl)-16-(4-hydroxyphenyl)-6-(2-(methylthio)ethyl)-5,8,11,14-tetraoxo-4,7,10,13-tetraazahexadecanoic acid


InChi Code: InChI=1S/C40H48N8O9S/c1-58-16-15-30(38(55)48-33(20-35(51)52)40(57)47-31(36(42)53)18-23-7-3-2-4-8-23)46-39(56)32(19-25-21-43-29-10-6-5-9-27(25)29)45-34(50)22-44-37(54)28(41)17-24-11-13-26(49)14-12-24/h2-14,21,28,30-33,43,49H,15-20,22,41H2,1H3,(H2,42,53)(H,44,54)(H,45,50)(H,46,56)(H,47,57)(H,48,55)(H,51,52)/t28-,30-,31-,32-,33-/m0/s1

SMILES Code: O=C(N)[C@H](CC1=CC=CC=C1)NC([C@H](CC(O)=O)NC([C@H](CCSC)NC([C@H](CC2=CNC3=C2C=CC=C3)NC(CNC([C@H](CC4=CC=C(O)C=C4)N)=O)=O)=O)=O)=O

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Gregory RA, Dockray GJ, Reeve JR Jr, Shively JE, Miller C. Isolation from porcine antral mucosa of a hexapeptide corresponding to the C-terminal sequence of gastrin. Peptides. 1983 May-Jun;4(3):319-23. PubMed PMID: 6634471.

2: Pincus MR, Carty RP, Chen J, Lubowsky J, Avitable M, Shah D, Scheraga HA, Murphy RB. On the biologically active structures of cholecystokinin, little gastrin, and enkephalin in the gastrointestinal system. Proc Natl Acad Sci U S A. 1987 Jul;84(14):4821-5. PubMed PMID: 3037525; PubMed Central PMCID: PMC305197.

3: Copps J, Ahmed S, Murphy RF, Lovas S. Gastrin 1-6 promotes growth of colon cancer cells through non-CCK receptors. Peptides. 2007 Mar;28(3):632-5. Epub 2006 Nov 28. PubMed PMID: 17126952.

4: Pincus MR, Murphy RB, Carty RP, Chen J, Shah D, Scheraga HA. Conformational analysis of possible biologically active (receptor-bound) conformations of peptides derived from cholecystokinin, cerulein and little gastrin and the opiate peptide, Met-enkephalin. Peptides. 1988;9 Suppl 1:145-52. PubMed PMID: 2856638.