Napropamide-M

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 597649

CAS#: 41643-35-0

Description: Napropamide-M is a herbicide.

Chemical Structure

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Napropamide-M
CAS# 41643-35-0
Instruction

Theoretical Analysis

MedKoo Cat#: 597649
Name: Napropamide-M
CAS#: 41643-35-0
Chemical Formula: C17H21NO2
Exact Mass: 271.16
Molecular Weight: 271.360
Elemental Analysis: C, 75.25; H, 7.80; N, 5.16; O, 11.79

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Napropamide-M; (R)-Devrinol; D-Napropamide;

IUPAC/Chemical Name: (R)-N,N-diethyl-2-(naphthalen-1-yloxy)propanamide

InChi Key: WXZVAROIGSFCFJ-CYBMUJFWSA-N

InChi Code: InChI=1S/C17H21NO2/c1-4-18(5-2)17(19)13(3)20-16-12-8-10-14-9-6-7-11-15(14)16/h6-13H,4-5H2,1-3H3/t13-/m1/s1

SMILES Code: C[C@@H](OC1=C2C=CC=CC2=CC=C1)C(N(CC)CC)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 271.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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6: Zhang C, Wu XM, Long YH, Li M, Li RY, Yin XH. [Identification and degradation characteristics of a napropamide-degrading bacterium strain]. Ying Yong Sheng Tai Xue Bao. 2016 Oct;27(10):3371-3378. doi: 10.13287/j.1001-9332.201610.017. Chinese. PubMed PMID: 29726165.

7: Zhang R, Cui J, Zhu HM, Yang H. Effect of dissolved organic matters on napropamide availability and ecotoxicity in rapeseed ( Brassica napus ). J Agric Food Chem. 2010 Mar 10;58(5):3232-40. doi: 10.1021/jf9027766. PubMed PMID: 20143852.

8: Guo H, Chen G, Lv Z, Zhao H, Yang H. Alteration of microbial properties and community structure in soils exposed to napropamide. J Environ Sci (China). 2009;21(4):494-502. PubMed PMID: 19634425.

9: Cui J, Zhang R, Wu GL, Zhu HM, Yang H. Salicylic acid reduces napropamide toxicity by preventing its accumulation in rapeseed (Brassica napus L.). Arch Environ Contam Toxicol. 2010 Jul;59(1):100-8. doi: 10.1007/s00244-009-9426-4. Epub 2009 Dec 5. PubMed PMID: 19967348.

10: Xie J, Zhao L, Liu K, Guo F, Liu W. Enantioseparation of four amide herbicide stereoisomers using high-performance liquid chromatography. J Chromatogr A. 2016 Nov 4;1471:145-154. doi: 10.1016/j.chroma.2016.10.029. Epub 2016 Oct 13. PubMed PMID: 27760706.

11: Liu H, Dang Y, Zhang S, Liu H, Qu L, Liao X, Zhao Y, Wu Y. Determination of diphenamide, napropamide and metolachlor in tobacco by gel permeation chromatographic clean-up and high performance liquid chromatography. Ann Chim. 2005 May;95(5):369-74. PubMed PMID: 16477944.

12: Williams CF, Letey J, Farmer WJ. Molecular weight of dissolved organic matter-napropamide complex transported through soil columns. J Environ Qual. 2002 Mar-Apr;31(2):619-27. PubMed PMID: 11931454.

13: Pahari AK, Majumdar S, Mandal TK, Chakraborty AK, Bhattacharyya A, Chowdhury A. Toxico-kinetics, recovery, and metabolism of napropamide in goats following a single high-dose oral administration. J Agric Food Chem. 2001 Apr;49(4):1817-24. PubMed PMID: 11308331.

14: Da Silva JP, Bastos EV, Ferreira LF, Weiss RG. Surface photochemistry of the herbicide napropamide. The role of the media and environmental factors in directing the fates of intermediates. Photochem Photobiol Sci. 2008 Jan;7(1):69-75. doi: 10.1039/b713369c. Epub 2007 Oct 31. PubMed PMID: 18167599.

15: Antonious GF, Patterson MA. Napropamide residues in runoff and infiltration water from pepper production. J Environ Sci Health B. 2005;40(3):385-96. PubMed PMID: 15913012.

16: Guo H, Zhu HM, Yang H. [Degradation and adsorption behavior of napropamide in soils]. Huan Jing Ke Xue. 2008 Jun;29(6):1729-36. Chinese. PubMed PMID: 18763531.

17: Salinas-Castillo A, Fernández-Sanchez JF, Segura-Carretero A, Fernández-Gutiérrez A. Simple determination of the herbicide napropamide in water and soil samples by room temperature phosphorescence. Pest Manag Sci. 2005 Aug;61(8):816-20. PubMed PMID: 15838936.

18: Biswas PK, Pramanik SK, Mitra SR, Bhattacharyya A. Persistence of napropamide in/on tea under North-East Indian climatic condition. Bull Environ Contam Toxicol. 2007 Nov;79(5):566-9. Epub 2007 Oct 9. PubMed PMID: 17924045.

19: Li YN, Wu HL, Qing XD, Nie CC, Li SF, Yu YJ, Zhang SR, Yu RQ. The maintenance of the second-order advantage: second-order calibration of excitation-emission matrix fluorescence for quantitative analysis of herbicide napropamide in various environmental samples. Talanta. 2011 Jul 15;85(1):325-32. doi: 10.1016/j.talanta.2011.03.067. Epub 2011 Apr 5. PubMed PMID: 21645706.

20: Chen SW, Cai XY, Xi M, Zhang AP, Liu WP. [Characterization of napropamide enantiomers by CD and determination of the enantiomeric ratios in water]. Guang Pu Xue Yu Guang Pu Fen Xi. 2006 Sep;26(9):1649-52. Chinese. PubMed PMID: 17112038.