WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 597631
CAS#: 99291-20-0
Description: V-9-M Cholecystokinin nonapeptide is a putative neuropeptide derived from procholecystokinin.
MedKoo Cat#: 597631
Name: V-9-M Cholecystokinin nonapeptide
CAS#: 99291-20-0
Chemical Formula: C42H69N9O14S
Exact Mass: 955.4685
Molecular Weight: 956.12
Elemental Analysis: C, 52.76; H, 7.27; N, 13.18; O, 23.43; S, 3.35
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Synonym: V-9-M Cholecystokinin nonapeptide; V-9-M; V 9 M; V9M; Val-pro-val-glu-ala-val-asp-pro-met;
IUPAC/Chemical Name: (S)-4-((S)-2-((S)-1-(L-valyl)pyrrolidine-2-carboxamido)-3-methylbutanamido)-5-(((S)-1-(((S)-1-(((S)-3-carboxy-1-((S)-2-(((S)-1-carboxy-3-(methylthio)propyl)carbamoyl)pyrrolidin-1-yl)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)amino)-1-oxopropan-2-yl)amino)-5-oxopentanoic acid
InChi Key: AIKMAJWJXJPJNB-HAMGYPHNSA-N
InChi Code: InChI=1S/C42H69N9O14S/c1-20(2)31(43)41(63)51-17-10-12-28(51)37(59)49-33(22(5)6)38(60)45-24(13-14-29(52)53)35(57)44-23(7)34(56)48-32(21(3)4)39(61)47-26(19-30(54)55)40(62)50-16-9-11-27(50)36(58)46-25(42(64)65)15-18-66-8/h20-28,31-33H,9-19,43H2,1-8H3,(H,44,57)(H,45,60)(H,46,58)(H,47,61)(H,48,56)(H,49,59)(H,52,53)(H,54,55)(H,64,65)/t23-,24-,25-,26-,27-,28-,31-,32-,33-/m0/s1
SMILES Code: CSCC[C@@H](C(O)=O)NC([C@H]1N(C([C@H](CC(O)=O)NC([C@H](C(C)C)NC([C@H](C)NC([C@H](CCC(O)=O)NC([C@H](C(C)C)NC([C@H]2N(C([C@H](C(C)C)N)=O)CCC2)=O)=O)=O)=O)=O)=O)CCC1)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 956.12 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Takashima A, Itoh S. Neuropharmacological properties of V-9-M, a putative neuropeptide derived from procholecystokinin, in the rat. Can J Physiol Pharmacol. 1989 Mar;67(3):223-7. PubMed PMID: 2501013.
2: Takashima A, Itoh S. Effect of V-9-M, a peptide fragment derived from procholecystokinin, on memory processes in the rat. Can J Physiol Pharmacol. 1989 Mar;67(3):228-31. PubMed PMID: 2743209.
3: Cao G, Beinfeld MC. Calcium-dependent pro-cholecystokinin V-9-M immunoreactive peptide release from rat brain slices and CCK-secreting rat medullary thyroid carcinoma cells in culture. Peptides. 1992 Nov-Dec;13(6):1087-90. PubMed PMID: 1494490.
4: Itoh S, Takashima A. Neuropharmacological profile of V-9-M, a putative neuropeptide derived from procholecystokinin. Prog Neurobiol. 1990;34(5):429-36. Review. PubMed PMID: 2192395.
