V-9-M Cholecystokinin nonapeptide

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 597631

CAS#: 99291-20-0

Description: V-9-M Cholecystokinin nonapeptide is a putative neuropeptide derived from procholecystokinin.


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V-9-M Cholecystokinin nonapeptide is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 597631
Name: V-9-M Cholecystokinin nonapeptide
CAS#: 99291-20-0
Chemical Formula: C42H69N9O14S
Exact Mass: 955.4685
Molecular Weight: 956.12
Elemental Analysis: C, 52.76; H, 7.27; N, 13.18; O, 23.43; S, 3.35


Synonym: V-9-M Cholecystokinin nonapeptide; V-9-M; V 9 M; V9M; Val-pro-val-glu-ala-val-asp-pro-met;

IUPAC/Chemical Name: (S)-4-((S)-2-((S)-1-(L-valyl)pyrrolidine-2-carboxamido)-3-methylbutanamido)-5-(((S)-1-(((S)-1-(((S)-3-carboxy-1-((S)-2-(((S)-1-carboxy-3-(methylthio)propyl)carbamoyl)pyrrolidin-1-yl)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)amino)-1-oxopropan-2-yl)amino)-5-oxopentanoic acid

InChi Key: AIKMAJWJXJPJNB-HAMGYPHNSA-N

InChi Code: InChI=1S/C42H69N9O14S/c1-20(2)31(43)41(63)51-17-10-12-28(51)37(59)49-33(22(5)6)38(60)45-24(13-14-29(52)53)35(57)44-23(7)34(56)48-32(21(3)4)39(61)47-26(19-30(54)55)40(62)50-16-9-11-27(50)36(58)46-25(42(64)65)15-18-66-8/h20-28,31-33H,9-19,43H2,1-8H3,(H,44,57)(H,45,60)(H,46,58)(H,47,61)(H,48,56)(H,49,59)(H,52,53)(H,54,55)(H,64,65)/t23-,24-,25-,26-,27-,28-,31-,32-,33-/m0/s1

SMILES Code: CSCC[C@@H](C(O)=O)NC([C@H]1N(C([C@H](CC(O)=O)NC([C@H](C(C)C)NC([C@H](C)NC([C@H](CCC(O)=O)NC([C@H](C(C)C)NC([C@H]2N(C([C@H](C(C)C)N)=O)CCC2)=O)=O)=O)=O)=O)=O)CCC1)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.03.00


References

1: Takashima A, Itoh S. Neuropharmacological properties of V-9-M, a putative neuropeptide derived from procholecystokinin, in the rat. Can J Physiol Pharmacol. 1989 Mar;67(3):223-7. PubMed PMID: 2501013.

2: Takashima A, Itoh S. Effect of V-9-M, a peptide fragment derived from procholecystokinin, on memory processes in the rat. Can J Physiol Pharmacol. 1989 Mar;67(3):228-31. PubMed PMID: 2743209.

3: Cao G, Beinfeld MC. Calcium-dependent pro-cholecystokinin V-9-M immunoreactive peptide release from rat brain slices and CCK-secreting rat medullary thyroid carcinoma cells in culture. Peptides. 1992 Nov-Dec;13(6):1087-90. PubMed PMID: 1494490.

4: Itoh S, Takashima A. Neuropharmacological profile of V-9-M, a putative neuropeptide derived from procholecystokinin. Prog Neurobiol. 1990;34(5):429-36. Review. PubMed PMID: 2192395.