WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 597597
CAS#: 92355-88-9
Description: N-Acylkansosamine is a N-acylamino sugar from trehalose-containing lipopolysaccharide antigens of Mycobacterium kansasii.
MedKoo Cat#: 597597
Name: N-Acylkansosamine
CAS#: 92355-88-9
Chemical Formula: C12H23NO6
Exact Mass: 277.1525
Molecular Weight: 277.31
Elemental Analysis: C, 51.97; H, 8.36; N, 5.05; O, 34.62
This product is not in stock, which may be available by custom synthesis.
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Synonym: N-Acylkansosamine;
IUPAC/Chemical Name: N-((2S,3S,4R,5R)-2,4-dihydroxy-5-methoxy-4-methyl-6-oxohexan-3-yl)-2-methoxypropanamide
InChi Key: KHYJVZNVWDCCAY-HIVFNARLSA-N
InChi Code: InChI=1S/C12H23NO6/c1-7(15)10(13-11(16)8(2)18-4)12(3,17)9(6-14)19-5/h6-10,15,17H,1-5H3,(H,13,16)/t7-,8?,9-,10-,12-/m0/s1
SMILES Code: O=C[C@@H]([C@]([C@@H](NC(C(OC)C)=O)[C@H](C)O)(C)O)OC
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 277.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Hunter SW, Fujiwara T, Murphy RC, Brennan PJ. N-acylkansosamine. A novel N-acylamino sugar from the trehalose-containing lipooligosaccharide antigens of Mycobacterium kansasii. J Biol Chem. 1984 Aug 10;259(15):9729-34. PubMed PMID: 6547719.
2: McNeil M, Gaylord H, Brennan PJ. N-formylkansosaminyl-(1----3)-2-O-methyl-D-rhamnopyranose: the type-specific determinant of serovariant 14 of the Mycobacterium avium complex. Carbohydr Res. 1988 Jun 15;177:185-98. PubMed PMID: 2458834.
3: Romero M, Diggle SP, Heeb S, Cámara M, Otero A. Quorum quenching activity in Anabaena sp. PCC 7120: identification of AiiC, a novel AHL-acylase. FEMS Microbiol Lett. 2008 Mar;280(1):73-80. doi: 10.1111/j.1574-6968.2007.01046.x. Epub 2008 Jan 9. PubMed PMID: 18194337.
