F-Chemotactic peptide-fluorescein

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 597586

CAS#: 117576-09-7

Description: F-Chemotactic peptide-fluorescein is a fluorescent label.


Chemical Structure

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F-Chemotactic peptide-fluorescein
CAS# 117576-09-7

Theoretical Analysis

MedKoo Cat#: 597586
Name: F-Chemotactic peptide-fluorescein
CAS#: 117576-09-7
Chemical Formula: C64H76N8O14S
Exact Mass: 1212.5202
Molecular Weight: 1213.41
Elemental Analysis: C, 63.35; H, 6.31; N, 9.23; O, 18.46; S, 2.64

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: F-Chemotactic peptide-fluorescein; Fnlpntl-fluorescein; N-Formyl-nle-leu-phe-nle-tyr-lys-fluorescein;

IUPAC/Chemical Name: N6-((3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-4-yl)carbamothioyl)-N2-(((S)-2-((S)-2-((S)-2-((S)-2-formamidohexanamido)-4-methylpentanamido)-3-phenylpropanamido)hexanoyl)-L-tyrosyl)-L-lysine

InChi Key: SZERHIDJPVWUOG-UTEXNEJUSA-N

InChi Code: InChI=1S/C64H76N8O14S/c1-5-7-18-47(66-36-73)56(77)69-50(31-37(3)4)58(79)71-51(32-38-15-10-9-11-16-38)59(80)67-48(19-8-6-2)57(78)70-52(33-39-22-24-40(74)25-23-39)60(81)68-49(61(82)83)20-12-13-30-65-63(87)72-46-21-14-17-45-55(46)62(84)86-64(45)43-28-26-41(75)34-53(43)85-54-35-42(76)27-29-44(54)64/h9-11,14-17,21-29,34-37,47-52,74-76H,5-8,12-13,18-20,30-33H2,1-4H3,(H,66,73)(H,67,80)(H,68,81)(H,69,77)(H,70,78)(H,71,79)(H,82,83)(H2,65,72,87)/t47-,48-,49-,50-,51-,52-/m0/s1

SMILES Code: O=C1OC2(c3ccc(O)cc3Oc4cc(O)ccc42)c5cccc(NC(NCCCC[C@@H](C(O)=O)NC([C@H](Cc6ccc(O)cc6)NC([C@H](CCCC)NC([C@H](Cc7ccccc7)NC([C@H](CC(C)C)NC([C@H](CCCC)NC=O)=O)=O)=O)=O)=O)=S)c15

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 1213.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Werner K, Kälble S, Wolter S, Schneider EH, Buschauer A, Neumann D, Seifert R. Flow cytometric analysis with a fluorescently labeled formyl peptide receptor ligand as a new method to study the pharmacological profile of the histamine H2 receptor. Naunyn Schmiedebergs Arch Pharmacol. 2015 Oct;388(10):1039-52. doi: 10.1007/s00210-015-1133-2. Epub 2015 May 30. PubMed PMID: 26021872.

2: Coppi M, Niederman R. Effects of ammonia on human neutrophil N-formyl chemotactic peptide receptor-ligand interaction and cytoskeletal association. Biochem Biophys Res Commun. 1989 Nov 30;165(1):377-83. PubMed PMID: 2590235.

3: Øie CI, Snapkov I, Elvevold K, Sveinbjørnsson B, Smedsrød B. FITC Conjugation Markedly Enhances Hepatic Clearance of N-Formyl Peptides. PLoS One. 2016 Aug 5;11(8):e0160602. doi: 10.1371/journal.pone.0160602. eCollection 2016. PubMed PMID: 27494406; PubMed Central PMCID: PMC4975464.

4: Hoffman JF, Keil ML, Riccobene TA, Omann GM, Linderman JJ. Interconverting receptor states at 4 degrees C for the neutrophil N-formyl peptide receptor. Biochemistry. 1996 Oct 8;35(40):13047-55. PubMed PMID: 8855940.

5: Hoffman JF, Linderman JJ, Omann GM. Receptor up-regulation, internalization, and interconverting receptor states. Critical components of a quantitative description of N-formyl peptide-receptor dynamics in the neutrophil. J Biol Chem. 1996 Aug 2;271(31):18394-404. PubMed PMID: 8702483.