L-742001 Hydrochloride
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 558372

CAS#: 174605-64-2

Description: L-742001 Hydrochloride is an inhibitor of RNA polymerase.


Price and Availability

Size
Price

5mg
USD 290
Size
Price

25mg
USD 750
Size
Price

L-742001 Hydrochloride, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

img

Theoretical Analysis

MedKoo Cat#: 558372
Name: L-742001 Hydrochloride
CAS#: 174605-64-2
Chemical Formula: C23H25Cl2NO4
Exact Mass: 449.12
Molecular Weight: 450.36
Elemental Analysis: C, 61.34; H, 5.60; Cl, 15.74; N, 3.11; O, 14.21


Related CAS #: 177592-42-6  

Synonym: L-742001; L 742001; L742001; L-742001 Hydrochloride; L 742001 Hydrochloride; L742001 Hydrochloride;

IUPAC/Chemical Name: 4-[4-[(4-Chlorophenyl)methyl]-1-(phenylmethyl)-4-piperidinyl]-2-hydroxy-4-oxo-2-butenoic acid Hydrochloride

InChi Key: LMLNSXCRZNNZBT-VSOKSMTPSA-N

InChi Code: InChI=1S/C23H24ClNO4.ClH/c24-19-8-6-17(7-9-19)15-23(21(27)14-20(26)22(28)29)10-12-25(13-11-23)16-18-4-2-1-3-5-18;/h1-9,14,26H,10-13,15-16H2,(H,28,29);1H/b20-14-;

SMILES Code: O=C(O)/C(O)=C/C(C1(CC2=CC=C(Cl)C=C2)CCN(CC3=CC=CC=C3)CC1)=O.[H]Cl


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.03.00


References

1: Yan Z, Zhang L, Fu H, Wang Z, Lin J. Design of the influenza virus inhibitors targeting the PA endonuclease using 3D-QSAR modeling, side-chain hopping, and docking. Bioorg Med Chem Lett. 2014 Jan 15;24(2):539-47. doi: 10.1016/j.bmcl.2013.12.026. Epub 2013 Dec 12. PubMed PMID: 24365156.