Valyllysine

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 597542

CAS#: 22677-62-9

Description: Valyllysine is a dipeptide composed of valine and lysine. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis.

Chemical Structure

img
Valyllysine
CAS# 22677-62-9
Instruction

Theoretical Analysis

MedKoo Cat#: 597542
Name: Valyllysine
CAS#: 22677-62-9
Chemical Formula: C11H23N3O3
Exact Mass: 245.17
Molecular Weight: 245.320
Elemental Analysis: C, 53.86; H, 9.45; N, 17.13; O, 19.56

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Valyllysine; Val-lys; Valyl-lysine;

IUPAC/Chemical Name: L-valyl-L-lysine

InChi Key: JKHXYJKMNSSFFL-IUCAKERBSA-N

InChi Code: InChI=1S/C11H23N3O3/c1-7(2)9(13)10(15)14-8(11(16)17)5-3-4-6-12/h7-9H,3-6,12-13H2,1-2H3,(H,14,15)(H,16,17)/t8-,9-/m0/s1

SMILES Code: NCCCC[C@@H](C(O)=O)NC([C@H](C(C)C)N)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 245.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Abe H, Satoh M, Miyauchi S, Shuto S, Matsuda A, Kamo N. Conjugation of dipeptide to fluorescent dyes enhances its affinity for a dipeptide transporter (PEPT1) in human intestinal Caco-2 cells. Bioconjug Chem. 1999 Jan-Feb;10(1):24-31. PubMed PMID: 9893960.

2: Tateoka R, Abe H, Miyauchi S, Shuto S, Matsuda A, Kobayashi M, Miyazaki K, Kamo N. Significance of substrate hydrophobicity for recognition by an oligopeptide transporter (PEPT1). Bioconjug Chem. 2001 Jul-Aug;12(4):485-92. PubMed PMID: 11459451.

3: Yui N, Ooya T, Kawashima T, Saito Y, Tamai I, Sai Y, Tsuji A. Inhibitory effect of supramolecular polyrotaxane-dipeptide conjugates on digested peptide uptake via intestinal human peptide transporter. Bioconjug Chem. 2002 May-Jun;13(3):582-7. PubMed PMID: 12009949.

4: Yennawar HP, Natarajan S, Viswamitra MA. Crystal and molecular structure of L-valyl-L-lysine hydrochloride. Int J Pept Protein Res. 1991 Dec;38(6):569-73. PubMed PMID: 1819591.

5: Nguyen KA, Travis J, Potempa J. Does the importance of the C-terminal residues in the maturation of RgpB from Porphyromonas gingivalis reveal a novel mechanism for protein export in a subgroup of Gram-Negative bacteria? J Bacteriol. 2007 Feb;189(3):833-43. Epub 2006 Dec 1. PubMed PMID: 17142394; PubMed Central PMCID: PMC1797278.

6: von Dungen A, Vater J, Kleinkauf H. Biosynthesis of gramicidin S with the aid of dipeptides by gramicidin S synthetase. Eur J Biochem. 1976 Jul 15;66(3):623-6. PubMed PMID: 60236.