WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 563210
CAS#: 1338575-28-2
Description: WWL229 is a selective Ces3 inhibitor. It acts by inhibiting recombinant Ces3 but not Ces1f, ABHD6 or other tested serine hydrolases, and recapitulating the effects of WWL113 in adipocytes.
MedKoo Cat#: 563210
Name: WWL229
CAS#: 1338575-28-2
Chemical Formula: C16H22N2O5
Exact Mass: 322.1529
Molecular Weight: 322.36
Elemental Analysis: C, 59.62; H, 6.88; N, 8.69; O, 24.82
Synonym: WWL229; WWL-229; WWL 229;
IUPAC/Chemical Name: 4-Nitrophenyl 2-(3-methoxypropyl)piperidine-1-carboxylate
InChi Key: XVBRVSAGMWRVCK-UHFFFAOYSA-N
InChi Code: InChI=1S/C16H22N2O5/c1-22-12-4-6-13-5-2-3-11-17(13)16(19)23-15-9-7-14(8-10-15)18(20)21/h7-10,13H,2-6,11-12H2,1H3
SMILES Code: O=C(N1C(CCCOC)CCCC1)OC2=CC=C([N+]([O-])=O)C=C2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 322.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Soni KG, Lehner R, Metalnikov P, O'Donnell P, Semache M, Gao W, Ashman K, Pshezhetsky AV, Mitchell GA. Carboxylesterase 3 (EC 3.1.1.1) is a major adipocyte lipase. J Biol Chem. 2004 Sep 24;279(39):40683-9. Epub 2004 Jun 25. PubMed PMID: 15220344.
