MedKoo Biosciences

2-Hydroxypropiophenone
featured

WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 592038

CAS#: 5650-40-8

Description: 2-Hydroxypropiophenone is a biochemical.

Chemical Structure

2-Hydroxypropiophenone

CAS# 5650-40-8

Instruction

Theoretical Analysis

MedKoo Cat#: 592038
Name: 2-Hydroxypropiophenone
CAS#: 5650-40-8
Chemical Formula: C9H10O2
Exact Mass: 150.07
Molecular Weight: 150.180
Elemental Analysis: C, 71.98; H, 6.71; O, 21.31

Price and Availability

Size	Price	Availability
100mg	USD 280	2 Weeks
250mg	USD 460	2 Weeks
500mg	USD 800	2 Weeks
Bulk inquiry Welcome, Customer: Please do not inquire quote if your intended use is for a patient since our products are for research use and for chemical synthesis use, not for human use . For in-stock products, we listed price in the web page. You may inquire prices for which sizes were not listed. If no price is listed, this means the product is not in stock at the moment, which may be available via custom synthesis. For cost-effective reason, minimum order of 1g is requested (typically very expensive). The lead time is usually 2-4 months. Quote of less than 1g will not be provided. MedKoo may not offer quote for below reasons: (1) current available synthetic method appears to be extremely expensive which is obviously not affordable to most customers; (2) Key raw material to make the product is temporally not available; (3) DEA controlled substances; (4) the product is under patent protection in customer’s country.

Synonym: 2-Hydroxypropiophenone; AI3-20420; AI3 20420; AI320420

IUPAC/Chemical Name: 2-Hydroxypropiophenone

InChi Key: WLVPRARCUSRDNI-UHFFFAOYSA-N

InChi Code: InChI=1S/C9H10O2/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,10H,1H3

SMILES Code: CC(O)C(C1=CC=CC=C1)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Instruction:

View handling instruction

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 150.18 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt* g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1

Volume 1

Concentration 2

Volume 2

1: Li X, Zhang XY, Zhou J, Song J, Wang JG, Yong XY, Jia HH. [Degradation Characteristics and Metabolic Pathway of a Pyrene-Degrading Pseudomonas aeruginosa Strain]. Huan Jing Ke Xue. 2018 Apr 8;39(4):1794-1803. doi: 10.13227/j.hjkx.201708243. Chinese. PubMed PMID: 29965006.

2: Naik KK, Thangavel S, Alam A, Kumar S. Flavone Analogues as Antimicrobial Agents. Recent Pat Inflamm Allergy Drug Discov. 2017;11(1):53-63. doi: 10.2174/1872213X11666170119094702. PubMed PMID: 28103779.

3: Hrušková K, Potůčková E, Hergeselová T, Liptáková L, Hašková P, Mingas P, Kovaříková P, Šimůnek T, Vávrová K. Aroylhydrazone iron chelators: Tuning antioxidant and antiproliferative properties by hydrazide modifications. Eur J Med Chem. 2016 Sep 14;120:97-110. doi: 10.1016/j.ejmech.2016.05.015. Epub 2016 May 7. PubMed PMID: 27187862.

4: Tural S, Tural B, Demir AS. Heterofunctional Magnetic Metal-Chelate-Epoxy Supports for the Purification and Covalent Immobilization of Benzoylformate Decarboxylase From Pseudomonas Putida and Its Carboligation Reactivity. Chirality. 2015 Sep;27(9):635-42. doi: 10.1002/chir.22477. Epub 2015 Jul 3. PubMed PMID: 26147067.

5: Seth P, Giri S, Ghosh A. Tuning of exchange coupling by the Mn-O distance and phenoxido bridging angle: an experimental and theoretical study of the family of Mn(iii) dimers with salen type ligands. Dalton Trans. 2015 Jul 28;44(28):12863-70. doi: 10.1039/c5dt01224d. PubMed PMID: 26102087.

6: Hailes HC, Rother D, Müller M, Westphal R, Ward JM, Pleiss J, Vogel C, Pohl M. Engineering stereoselectivity of ThDP-dependent enzymes. FEBS J. 2013 Dec;280(24):6374-94. doi: 10.1111/febs.12496. Epub 2013 Sep 13. Review. PubMed PMID: 24034356.

7: Kulig J, Frese A, Kroutil W, Pohl M, Rother D. Biochemical characterization of an alcohol dehydrogenase from Ralstonia sp. Biotechnol Bioeng. 2013 Jul;110(7):1838-48. doi: 10.1002/bit.24857. Epub 2013 Feb 22. PubMed PMID: 23381774.

8: Krizevski R, Bar E, Shalit OR, Levy A, Hagel JM, Kilpatrick K, Marsolais F, Facchini PJ, Ben-Shabat S, Sitrit Y, Lewinsohn E. Benzaldehyde is a precursor of phenylpropylamino alkaloids as revealed by targeted metabolic profiling and comparative biochemical analyses in Ephedra spp. Phytochemistry. 2012 Sep;81:71-9. doi: 10.1016/j.phytochem.2012.05.018. Epub 2012 Jun 21. PubMed PMID: 22727117.

9: Inglis R, Stoumpos CC, Prescimone A, Siczek M, Lis T, Wernsdorfer W, Brechin EK, Milios CJ. Ferromagnetic manganese "cubes": from PSII to single-molecule magnets. Dalton Trans. 2010 May 28;39(20):4777-85. PubMed PMID: 21491644.

10: Mason K, Gass IA, White FJ, Papaefstathiou GS, Brechin EK, Tasker PA. Hexa- and octanuclear iron(III) salicylaldoxime clusters. Dalton Trans. 2011 Mar 28;40(12):2875-81. doi: 10.1039/c0dt01593h. Epub 2011 Feb 10. PubMed PMID: 21308137.

11: Kara S, Long WS, Berheide M, Peper S, Niemeyer B, Liese A. Influence of reaction conditions on the enantioselectivity of biocatalyzed C-C bond formations under high pressure conditions. J Biotechnol. 2011 Mar 20;152(3):87-92. doi: 10.1016/j.jbiotec.2011.01.020. Epub 2011 Feb 3. PubMed PMID: 21295624.

12: Peper S, Kara S, Long WS, Liese A, Niemeyer B. Immobilization and characterization of benzoylformate decarboxylase from Pseudomonas putida on spherical silica carrier. Bioprocess Biosyst Eng. 2011 Aug;34(6):671-80. doi: 10.1007/s00449-011-0516-0. Epub 2011 Feb 1. PubMed PMID: 21286757.

13: Kozoni C, Manolopoulou E, Siczek M, Lis T, Brechin EK, Milios CJ. Polynuclear manganese amino acid complexes. Dalton Trans. 2010 Sep 14;39(34):7943-50. doi: 10.1039/c0dt00192a. Epub 2010 Aug 3. PubMed PMID: 20680216.

14: Berheide M, Peper S, Kara S, Long WS, Schenkel S, Pohl M, Niemeyer B, Liese A. Influence of the hydrostatic pressure and pH on the asymmetric 2-hydroxyketone formation catalyzed by Pseudomonas putida benzoylformate decarboxylase and variants thereof. Biotechnol Bioeng. 2010 May 1;106(1):18-26. doi: 10.1002/bit.22650. PubMed PMID: 20047192.

15: Gass IA, Milios CJ, Collins A, White FJ, Budd L, Parsons S, Murrie M, Perlepes SP, Brechin EK. Polymetallic clusters of iron(III) with derivatised salicylaldoximes. Dalton Trans. 2008 Apr 21;(15):2043-53. doi: 10.1039/b717534e. Epub 2008 Feb 19. PubMed PMID: 18382782.

16: Milios CJ, Inglis R, Vinslava A, Bagai R, Wernsdorfer W, Parsons S, Perlepes SP, Christou G, Brechin EK. Toward a magnetostructural correlation for a family of Mn6 SMMs. J Am Chem Soc. 2007 Oct 17;129(41):12505-11. Epub 2007 Sep 22. PubMed PMID: 17887755.

17: Milios CJ, Vinslava A, Wernsdorfer W, Prescimone A, Wood PA, Parsons S, Perlepes SP, Christou G, Brechin EK. Spin switching via targeted structural distortion. J Am Chem Soc. 2007 May 23;129(20):6547-61. Epub 2007 Apr 26. PubMed PMID: 17458963.

18: Siegert P, McLeish MJ, Baumann M, Iding H, Kneen MM, Kenyon GL, Pohl M. Exchanging the substrate specificities of pyruvate decarboxylase from Zymomonas mobilis and benzoylformate decarboxylase from Pseudomonas putida. Protein Eng Des Sel. 2005 Jul;18(7):345-57. Epub 2005 Jun 1. PubMed PMID: 15930043.

19: Pohl M, Siegert P, Mesch K, Bruhn H, Grötzinger J. Active site mutants of pyruvate decarboxylase from Zymomonas mobilis--a site-directed mutagenesis study of L112, I472, I476, E473, and N482. Eur J Biochem. 1998 Nov 1;257(3):538-46. PubMed PMID: 9839941.

20: Gala D, Puar MS, Das PR, Kugelman M, DiBenedetto DJ. Decomposition of alpha-hydroxyaryl ketones and characterization of some unusual products. J Pharm Sci. 1992 Dec;81(12):1199-203. PubMed PMID: 1491340.

Your view history

2-Hydroxypropiophenone featured