WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 597462
Description: Ici 174865 is a delta opioid receptor antagonist.
MedKoo Cat#: 597462
Name: Ici 174865
Chemical Formula: C38H53N5O7
Exact Mass: 691.3945
Molecular Weight: 691.87
Elemental Analysis: C, 65.97; H, 7.72; N, 10.12; O, 16.19
This product is not in stock, which may be available by custom synthesis.
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Synonym: Ici 174865; Ici-174865; Ici174865; Ici 174,865; Ici-174,865; Iciq174,865;
IUPAC/Chemical Name: (2-(2-((S)-2-(diallylamino)-3-(4-hydroxyphenyl)propanamido)-2-methylpropanamido)-2-methylpropanoyl)-L-phenylalanyl-L-leucine
InChi Key: XUWLAGNFLUARAN-CHQNGUEUSA-N
InChi Code: InChI=1S/C38H53N5O7/c1-9-20-43(21-10-2)31(24-27-16-18-28(44)19-17-27)33(46)41-38(7,8)36(50)42-37(5,6)35(49)40-29(23-26-14-12-11-13-15-26)32(45)39-30(34(47)48)22-25(3)4/h9-19,25,29-31,44H,1-2,20-24H2,3-8H3,(H,39,45)(H,40,49)(H,41,46)(H,42,50)(H,47,48)/t29-,30-,31-/m0/s1
SMILES Code: CC(C)C[C@@H](C(O)=O)NC([C@H](CC1=CC=CC=C1)NC(C(C)(C)NC(C(C)(C)NC([C@H](CC2=CC=C(O)C=C2)N(CC=C)CC=C)=O)=O)=O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 691.87 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Ableitner A. Brain sites involved in delta-opioid receptor-mediated actions. Eur J Pharmacol. 1994 Dec 12;271(1):213-22. PubMed PMID: 7698203.
2: Calvo CF, Cesselin F, Gelman M, Glowinski J. Identification of an opioid peptide secreted by rat embryonic mixed brain cells as a promoter of macrophage migration. Eur J Neurosci. 2000 Aug;12(8):2676-84. PubMed PMID: 10971611.
3: Maslov LN, Krylatov AV, Lishmanov AIu, Podoksenov IuK, Solenkova NV, Bogomaz SA, Tam SW, Gross GJ. [Stimulation of peripheral delta1-opioid receptors as a method of preventing ischemic and reperfusion arrhythmia: role of K(ATP)-channels]. Eksp Klin Farmakol. 2001 Nov-Dec;64(6):27-30. Russian. PubMed PMID: 11871232.