Ici 174865

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MedKoo CAT#: 597462

CAS#: 92535-15-4

Description: Ici 174865 is a delta opioid receptor antagonist.

Chemical Structure

Ici 174865
CAS# 92535-15-4

Theoretical Analysis

MedKoo Cat#: 597462
Name: Ici 174865
CAS#: 92535-15-4
Chemical Formula: C38H53N5O7
Exact Mass: 691.3945
Molecular Weight: 691.87
Elemental Analysis: C, 65.97; H, 7.72; N, 10.12; O, 16.19

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Ici 174865; Ici-174865; Ici174865; Ici 174,865; Ici-174,865; Iciq174,865;

IUPAC/Chemical Name: (2-(2-((S)-2-(diallylamino)-3-(4-hydroxyphenyl)propanamido)-2-methylpropanamido)-2-methylpropanoyl)-L-phenylalanyl-L-leucine


InChi Code: InChI=1S/C38H53N5O7/c1-9-20-43(21-10-2)31(24-27-16-18-28(44)19-17-27)33(46)41-38(7,8)36(50)42-37(5,6)35(49)40-29(23-26-14-12-11-13-15-26)32(45)39-30(34(47)48)22-25(3)4/h9-19,25,29-31,44H,1-2,20-24H2,3-8H3,(H,39,45)(H,40,49)(H,41,46)(H,42,50)(H,47,48)/t29-,30-,31-/m0/s1

SMILES Code: CC(C)C[C@@H](C(O)=O)NC([C@H](CC1=CC=CC=C1)NC(C(C)(C)NC(C(C)(C)NC([C@H](CC2=CC=C(O)C=C2)N(CC=C)CC=C)=O)=O)=O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 691.87 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Ableitner A. Brain sites involved in delta-opioid receptor-mediated actions. Eur J Pharmacol. 1994 Dec 12;271(1):213-22. PubMed PMID: 7698203.

2: Calvo CF, Cesselin F, Gelman M, Glowinski J. Identification of an opioid peptide secreted by rat embryonic mixed brain cells as a promoter of macrophage migration. Eur J Neurosci. 2000 Aug;12(8):2676-84. PubMed PMID: 10971611.

3: Maslov LN, Krylatov AV, Lishmanov AIu, Podoksenov IuK, Solenkova NV, Bogomaz SA, Tam SW, Gross GJ. [Stimulation of peripheral delta1-opioid receptors as a method of preventing ischemic and reperfusion arrhythmia: role of K(ATP)-channels]. Eksp Klin Farmakol. 2001 Nov-Dec;64(6):27-30. Russian. PubMed PMID: 11871232.