BCH 2763

We are open as normal during COVID-19 pandemic. Order online, same day shipping out from North Carolina, USA

WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 597427

CAS#: 204641-27-0

Description: BCH 2763 is a potent, selective bifunctional thrombin inhibitor that blocks both the active catalytic site and the anion binding exosite.

Price and Availability

Size	Price	Shipping out time	Quantity
Inquire bulk and customized quantity

Pricing updated 2020-10-19. Prices are subject to change without notice.

BCH 2763 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure

Theoretical Analysis

MedKoo Cat#: 597427
Name: BCH 2763
CAS#: 204641-27-0
Chemical Formula: C64H93N11O16
Exact Mass: 1271.6802
Molecular Weight: 1272.5
Elemental Analysis: C, 60.41; H, 7.37; N, 12.11; O, 20.12

Synonym: BCH 2763; BCH-2763; BCH2763;

IUPAC/Chemical Name: (S)-5-((S)-2-(((2S,3S)-1-((S)-2-((5-((S)-1-(D-phenylalanyl)pyrrolidine-2-carboxamido)pentanoyl)((S)-1-carboxy-3-methylbutyl)carbamoyl)pyrrolidin-1-yl)-3-methyl-1-oxopentan-2-yl)carbamoyl)pyrrolidin-1-yl)-4-((S)-2-((S)-2-(5-aminopentanamido)-3-carboxypropanamido)-3-phenylpropanamido)-5-oxopentanoic acid

InChi Key: VKIPOMGKUAJAEY-GEPLSBMPSA-N

InChi Code: InChI=1S/C64H93N11O16/c1-5-40(4)55(71-59(85)48-24-17-33-73(48)61(87)44(28-29-53(78)79)69-56(82)45(37-42-21-10-7-11-22-42)70-57(83)46(38-54(80)81)68-51(76)26-12-14-30-65)63(89)74-34-18-25-49(74)62(88)75(50(64(90)91)35-39(2)3)52(77)27-13-15-31-67-58(84)47-23-16-32-72(47)60(86)43(66)36-41-19-8-6-9-20-41/h6-11,19-22,39-40,43-50,55H,5,12-18,23-38,65-66H2,1-4H3,(H,67,84)(H,68,76)(H,69,82)(H,70,83)(H,71,85)(H,78,79)(H,80,81)(H,90,91)/t40-,43+,44-,45-,46-,47-,48-,49-,50-,55-/m0/s1

SMILES Code: CC(C)C[C@@H](C(O)=O)N(C(CCCCNC([C@H]1N(C([C@@H](CC2=CC=CC=C2)N)=O)CCC1)=O)=O)C([C@H]3N(C([C@H]([C@@H](C)CC)NC([C@H]4N(C([C@H](CCC(O)=O)NC([C@H](CC5=CC=CC=C5)NC([C@H](CC(O)=O)NC(CCCCN)=O)=O)=O)=O)CCC4)=O)=O)CCC3)=O

Technical Data

Appearance:

Solid powder

Purity:

>98% (or refer to the Certificate of Analysis)

Shipping Condition:

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:

Soluble in DMSO

Shelf Life:

>3 years if stored properly

Drug Formulation:

This drug may be formulated in DMSO

Stock Solution Storage:

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:

2934.99.03.00

References

1: McClanahan TB, Ignasiak DP, Juneau P, Finkle C, Winocour PD, Gallagher KP. Antithrombotic effects of BCH 2763, a new direct thrombin inhibitor, in a canine model of venous thrombosis. J Thromb Thrombolysis. 1999 Jun;7(3):301-6. PubMed PMID: 10375391.

2: Finkle CD, St Pierre A, Leblond L, Deschenes I, DiMaio J, Winocour PD. BCH-2763, a novel potent parenteral thrombin inhibitor, is an effective antithrombotic agent in rodent models of arterial and venous thrombosis--comparisons with heparin, r-hirudin, hirulog, inogatran and argatroban. Thromb Haemost. 1998 Feb;79(2):431-8. PubMed PMID: 9493603.

3: Deschênes I, Finkle CD, Winocour PD. Effective use of BCH-2763, a new potent injectable direct thrombin inhibitor, in combination with tissue plasminogen activator (tPA) in a rat arterial thrombolysis model. Thromb Haemost. 1998 Jul;80(1):186-91. PubMed PMID: 9684808.

All Products

Featured Products