BCH 2763

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MedKoo CAT#: 597427

CAS#: 204641-27-0

Description: BCH 2763 is a potent, selective bifunctional thrombin inhibitor that blocks both the active catalytic site and the anion binding exosite.

Price and Availability

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Pricing updated 2020-10-19. Prices are subject to change without notice.

BCH 2763 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 597427
Name: BCH 2763
CAS#: 204641-27-0
Chemical Formula: C64H93N11O16
Exact Mass: 1271.6802
Molecular Weight: 1272.5
Elemental Analysis: C, 60.41; H, 7.37; N, 12.11; O, 20.12

Synonym: BCH 2763; BCH-2763; BCH2763;

IUPAC/Chemical Name: (S)-5-((S)-2-(((2S,3S)-1-((S)-2-((5-((S)-1-(D-phenylalanyl)pyrrolidine-2-carboxamido)pentanoyl)((S)-1-carboxy-3-methylbutyl)carbamoyl)pyrrolidin-1-yl)-3-methyl-1-oxopentan-2-yl)carbamoyl)pyrrolidin-1-yl)-4-((S)-2-((S)-2-(5-aminopentanamido)-3-carboxypropanamido)-3-phenylpropanamido)-5-oxopentanoic acid


InChi Code: InChI=1S/C64H93N11O16/c1-5-40(4)55(71-59(85)48-24-17-33-73(48)61(87)44(28-29-53(78)79)69-56(82)45(37-42-21-10-7-11-22-42)70-57(83)46(38-54(80)81)68-51(76)26-12-14-30-65)63(89)74-34-18-25-49(74)62(88)75(50(64(90)91)35-39(2)3)52(77)27-13-15-31-67-58(84)47-23-16-32-72(47)60(86)43(66)36-41-19-8-6-9-20-41/h6-11,19-22,39-40,43-50,55H,5,12-18,23-38,65-66H2,1-4H3,(H,67,84)(H,68,76)(H,69,82)(H,70,83)(H,71,85)(H,78,79)(H,80,81)(H,90,91)/t40-,43+,44-,45-,46-,47-,48-,49-,50-,55-/m0/s1

SMILES Code: CC(C)C[C@@H](C(O)=O)N(C(CCCCNC([C@H]1N(C([C@@H](CC2=CC=CC=C2)N)=O)CCC1)=O)=O)C([C@H]3N(C([C@H]([C@@H](C)CC)NC([C@H]4N(C([C@H](CCC(O)=O)NC([C@H](CC5=CC=CC=C5)NC([C@H](CC(O)=O)NC(CCCCN)=O)=O)=O)=O)CCC4)=O)=O)CCC3)=O

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: McClanahan TB, Ignasiak DP, Juneau P, Finkle C, Winocour PD, Gallagher KP. Antithrombotic effects of BCH 2763, a new direct thrombin inhibitor, in a canine model of venous thrombosis. J Thromb Thrombolysis. 1999 Jun;7(3):301-6. PubMed PMID: 10375391.

2: Finkle CD, St Pierre A, Leblond L, Deschenes I, DiMaio J, Winocour PD. BCH-2763, a novel potent parenteral thrombin inhibitor, is an effective antithrombotic agent in rodent models of arterial and venous thrombosis--comparisons with heparin, r-hirudin, hirulog, inogatran and argatroban. Thromb Haemost. 1998 Feb;79(2):431-8. PubMed PMID: 9493603.

3: Deschênes I, Finkle CD, Winocour PD. Effective use of BCH-2763, a new potent injectable direct thrombin inhibitor, in combination with tissue plasminogen activator (tPA) in a rat arterial thrombolysis model. Thromb Haemost. 1998 Jul;80(1):186-91. PubMed PMID: 9684808.