WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 591920

CAS#: 123-30-8

Description: 4-Aminophenol (or para-aminophenol or p-aminophenol) is the organic compound with the formula H2NC6H4OH. Typically available as a white powder,[2] it was commonly used as a developer for black-and-white film, marketed under the name Rodinal.

Chemical Structure

CAS# 123-30-8

Theoretical Analysis

MedKoo Cat#: 591920
Name: 4-Aminophenol
CAS#: 123-30-8
Chemical Formula: C6H7NO
Exact Mass: 109.0528
Molecular Weight: 109.13
Elemental Analysis: Chemical Formula: C6H7NO Exact Mass: 109.0528 Molecular Weight: 109.1280 Elemental Analysis: C, 66.04; H, 6.47; N, 12.84; O, 14.66

Price and Availability

Size Price Availability Quantity
25.0g USD 220.0 2 Weeks
500.0g USD 380.0 2 Weeks
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Synonym: NSC 1545; NSC-1545; NSC1545; 4-Aminophenol

IUPAC/Chemical Name: 4-Aminophenol


InChi Code: InChI=1S/C6H7NO/c7-5-1-3-6(8)4-2-5/h1-4,8H,7H2


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 109.13 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

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1: Wacławek S, Gončuková Z, Adach K, Fijałkowski M, Černík M. Green synthesis of gold nanoparticles using Artemisia dracunculus extract: control of the shape and size by varying synthesis conditions. Environ Sci Pollut Res Int. 2018 Jun 12. doi: 10.1007/s11356-018-2510-4. [Epub ahead of print] PubMed PMID: 29948700.

2: Bouazizi N, Vieillard J, Thebault P, Desriac F, Clamens T, Bargougui R, Couvrat N, Thoumire O, Brun N, Ladam G, Morin S, Mofaddel N, Lesouhaitier O, Azzouz A, Le Derf F. Silver nanoparticle embedded copper oxide as an efficient core-shell for the catalytic reduction of 4-nitrophenol and antibacterial activity improvement. Dalton Trans. 2018 Jun 27. doi: 10.1039/c8dt02154f. [Epub ahead of print] PubMed PMID: 29946586.

3: Tian M, Thind SS, Dondapati JS, Li X, Chen A. Electrochemical oxidation of 4-chlorophenol for wastewater treatment using highly active UV treated TiO(2) nanotubes. Chemosphere. 2018 Jun 7;209:182-190. doi: 10.1016/j.chemosphere.2018.06.042. [Epub ahead of print] PubMed PMID: 29929124.

4: Yang X, Li Y, Zhang P, Zhou R, Peng H, Liu D, Gui J. Photoinduced in Situ Deposition of Uniform and Well-Dispersed PtO(2) Nanoparticles on ZnO Nanorods for Efficient Catalytic Reduction of 4-Nitrophenol. ACS Appl Mater Interfaces. 2018 Jun 26. doi: 10.1021/acsami.8b06815. [Epub ahead of print] PubMed PMID: 29912543.

5: Wang B, Wang H, Zhang F, Sun T. Preparation of Hierarchical Porous Silicalite-1 Encapsulated Ag NPs and Its Catalytic Performance for 4-Nitrophenol Reduction. Nanoscale Res Lett. 2018 Jun 7;13(1):174. doi: 10.1186/s11671-018-2579-1. PubMed PMID: 29881924; PubMed Central PMCID: PMC5992112.

6: Lee MJ, Kang SH, Dey J, Choi SM. Porous Silica-Coated Gold Sponges with High Thermal and Catalytic Stability. ACS Appl Mater Interfaces. 2018 Jun 25. doi: 10.1021/acsami.8b04811. [Epub ahead of print] PubMed PMID: 29806933.

7: Xu B, Chen BY, Huang KC, Sun QJ, Chi-Wei Lan J. Deciphering synergistic characteristics of redox mediators-stimulated echinenone production of Gordonia terrae TWIH01. J Biosci Bioeng. 2018 May 18. pii: S1389-1723(18)30098-7. doi: 10.1016/j.jbiosc.2018.03.019. [Epub ahead of print] PubMed PMID: 29784541.

8: Nabikhan A, Rathinam S, Kandasamy K. Biogenic gold nanoparticles for reduction of 4-nitrophenol to 4-aminophenol: an eco-friendly bioremediation. IET Nanobiotechnol. 2018 Jun;12(4):479-483. doi: 10.1049/iet-nbt.2017.0210. PubMed PMID: 29768233.

9: Sun J, Zhao J, Bao X, Wang Q, Yang X. Alkaline Phosphatase Assay Based on the Chromogenic Interaction of Diethanolamine with 4-Aminophenol. Anal Chem. 2018 May 15;90(10):6339-6345. doi: 10.1021/acs.analchem.8b01371. Epub 2018 Apr 26. PubMed PMID: 29683655.

10: Mohammadi Z, Entezari MH. Sono-synthesis approach in uniform loading of ultrafine Ag nanoparticles on reduced graphene oxide nanosheets: An efficient catalyst for the reduction of 4-Nitrophenol. Ultrason Sonochem. 2018 Jun;44:1-13. doi: 10.1016/j.ultsonch.2018.01.020. Epub 2018 Feb 7. PubMed PMID: 29680590.

11: Bhat SA, Rashid N, Rather MA, Pandit SA, Rather GM, Ingole PP, Bhat MA. PdAg Bimetallic Nanoalloy-Decorated Graphene: A Nanohybrid with Unprecedented Electrocatalytic, Catalytic, and Sensing Activities. ACS Appl Mater Interfaces. 2018 May 16;10(19):16376-16389. doi: 10.1021/acsami.8b00510. Epub 2018 May 2. PubMed PMID: 29658695.

12: Mansingh S, Acharya R, Martha S, Parida KM. Pyrochlore Ce(2)Zr(2)O(7) decorated over rGO: a photocatalyst that proves to be efficient towards the reduction of 4-nitrophenol and degradation of ciprofloxacin under visible light. Phys Chem Chem Phys. 2018 Apr 18;20(15):9872-9885. doi: 10.1039/c8cp00621k. PubMed PMID: 29619471.

13: Ranjith KS, Celebioglu A, Uyar T. Immobilized Pd-Ag bimetallic nanoparticles on polymeric nanofibers as an effective catalyst: effective loading of Ag with bimetallic functionality through Pd nucleated nanofibers. Nanotechnology. 2018 Jun 15;29(24):245602. doi: 10.1088/1361-6528/aab9da. Epub 2018 Mar 27. PubMed PMID: 29582779.

14: Dai Y, Zhu M, Wang X, Wu Y, Huang C, Fu W, Meng X, Sun Y. Visible-light promoted catalytic activity of dumbbell-like Au nanorods supported on graphene/TiO(2) sheets towards hydrogenation reaction. Nanotechnology. 2018 Jun 15;29(24):245703. doi: 10.1088/1361-6528/aab9c2. Epub 2018 Mar 27. PubMed PMID: 29581413.

15: Mubarak M, Jeon H, Islam MS, Yoon C, Bae JS, Hwang SJ, Choi WS, Lee HJ. One-pot synthesis of layered double hydroxide hollow nanospheres with ultrafast removal efficiency for heavy metal ions and organic contaminants. Chemosphere. 2018 Jun;201:676-686. doi: 10.1016/j.chemosphere.2018.03.046. Epub 2018 Mar 6. PubMed PMID: 29547856.

16: Zhang H, Yu K, Li N, He J, You H, Jiang J. Intermediate detection in real time using reactive surface desorption dielectric-barrier discharge ionization mass spectrometry. J Mass Spectrom. 2018 Jun;53(6):511-517. doi: 10.1002/jms.4080. Epub 2018 Apr 20. PubMed PMID: 29520925.

17: Fu F, Wang Q, Ciganda R, Martinez-Villacorta AM, Escobar A, Moya S, Fouquet E, Ruiz J, Astruc D. Electron- and Hydride-Reservoir Organometallics as Precursors of Catalytically Efficient Transition Metal Nanoparticles in Water. Chemistry. 2018 May 2;24(25):6645-6653. doi: 10.1002/chem.201800418. Epub 2018 Apr 14. PubMed PMID: 29488659.

18: Meng Y, Cai L, Xu X, Zhang L. Construction of size-controllable gold nanoparticles immobilized on polysaccharide nanotubes by in situ one-pot synthesis. Int J Biol Macromol. 2018 Jul 1;113:240-247. doi: 10.1016/j.ijbiomac.2018.02.122. Epub 2018 Feb 21. PubMed PMID: 29476855.

19: Kim TY, Park Y. Green Synthesis and Catalytic Activity of Gold Nanoparticles/Graphene Oxide Nanocomposites Prepared By Tannic Acid. J Nanosci Nanotechnol. 2018 Apr 1;18(4):2536-2546. doi: 10.1166/jnn.2018.14389. PubMed PMID: 29442924.

20: Zhao H, Zhao L. Magnetic N-doped Co-carbon composites derived from metal organic frameworks as highly efficient catalysts for p-nitrophenol reduction reaction. Dalton Trans. 2018 Mar 6;47(10):3321-3328. doi: 10.1039/c7dt04272h. PubMed PMID: 29423466.