Palmitoyl isoleucine

We are open as normal during COVID-19 pandemic. Order online, same day shipping out.

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 597377

CAS#: 54617-29-7

Description: Palmitoyl isoleucine is a lipo-aminoacid derived from the naturally occurring essential amino acid isoleucine that is known for its ability to support tissue repair and lift vital proteins on the skin.


Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-07-10. Prices are subject to change without notice.

Palmitoyl isoleucine is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

img

Theoretical Analysis

MedKoo Cat#: 597377
Name: Palmitoyl isoleucine
CAS#: 54617-29-7
Chemical Formula: C22H43NO3
Exact Mass: 369.3243
Molecular Weight: 369.59
Elemental Analysis: C, 71.50; H, 11.73; N, 3.79; O, 12.99


Synonym: Palmitoyl isoleucine; L-Isoleucine, N-(1-oxohexadecyl)-; Voluform;

IUPAC/Chemical Name: palmitoyl-L-isoleucine

InChi Key: NGYZAEAXQQNUBZ-FPOVZHCZSA-N

InChi Code: InChI=1S/C22H43NO3/c1-4-6-7-8-9-10-11-12-13-14-15-16-17-18-20(24)23-21(22(25)26)19(3)5-2/h19,21H,4-18H2,1-3H3,(H,23,24)(H,25,26)/t19-,21-/m0/s1

SMILES Code: CC[C@H](C)[C@@H](C(O)=O)NC(CCCCCCCCCCCCCCC)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.03.00


References

1: Ghosh A, Dobson ET, Buettner CJ, Nicholl MJ, Goldberger JE. Programming pH-triggered self-assembly transitions via isomerization of peptide sequence. Langmuir. 2014 Dec 30;30(51):15383-7. doi: 10.1021/la5037663. Epub 2014 Dec 17. PubMed PMID: 25474500.

2: Almlén A, Vandenbussche G, Linderholm B, Haegerstrand-Björkman M, Johansson J, Curstedt T. Alterations of the C-terminal end do not affect in vitro or in vivo activity of surfactant protein C analogs. Biochim Biophys Acta. 2012 Jan;1818(1):27-32. doi: 10.1016/j.bbamem.2011.01.013. Epub 2011 Jan 31. PubMed PMID: 21284935.

3: Kendall M. Fine airborne urban particles (PM2.5) sequester lung surfactant and amino acids from human lung lavage. Am J Physiol Lung Cell Mol Physiol. 2007 Oct;293(4):L1053-8. Epub 2007 Jul 6. PubMed PMID: 17616648.

4: Ravandi A, Kuksis A, Shaikh N, Jackowski G. Preparation of Schiff base adducts of phosphatidylcholine core aldehydes and aminophospholipids, amino acids, and myoglobin. Lipids. 1997 Sep;32(9):989-1001. PubMed PMID: 9307942.

5: Sankaram MB, Jones JD. Mode of membrane interaction of wild-type and mutant signal peptides of the Escherichia coli outer membrane protein A. J Biol Chem. 1994 Sep 23;269(38):23477-83. PubMed PMID: 8089113.

6: Berchiche L, Legrand C, Capiaumont J, Belleville F, Nabet P. Effect of L-carnitine and acylcarnitine derivatives on the proliferation and monoclonal antibody production of mouse hybridoma cells in culture. J Biotechnol. 1994 May 15;34(2):175-83. PubMed PMID: 7764849.

7: Lewis DF, Lake BG. Interaction of some peroxisome proliferators with the mouse liver peroxisome proliferator-activated receptor (PPAR): a molecular modelling and quantitative structure-activity relationship (QSAR) study. Xenobiotica. 1993 Jan;23(1):79-96. PubMed PMID: 8387235.

8: Fedotcheva NI, Gessler NN, Bykhovskiĭ VIa, Kondrashova MN. [The effect of metabolites of the propionate pathway on the oxidative activity of liver mitochondria]. Biokhimiia. 1991 Mar;56(3):426-33. Russian. PubMed PMID: 1883904.

9: Vial HJ, Ancelin ML, Thuet MJ, Philippot JR. Differential effects of chloroquine on the phospholipid metabolism of Plasmodium-infected erythrocytes. Biochem Pharmacol. 1988 Aug 15;37(16):3139-47. PubMed PMID: 3401244.

10: Ikeda Y, Tanaka K. Purification and characterization of 2-methyl-branched chain acyl coenzyme A dehydrogenase, an enzyme involved in the isoleucine and valine metabolism, from rat liver mitochondria. J Biol Chem. 1983 Aug 10;258(15):9477-87. PubMed PMID: 6874697.