Glutaurine

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 597281

CAS#: 56488-60-9

Description: Glutaurine is a recently deteccted hormone of parathyroid gland. Glutaurine has been observed to display antiepileptic effects with anti-amnesia properties. Mimics anxiolytic drug Diazepam.

Chemical Structure

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Glutaurine
CAS# 56488-60-9
Instruction

Theoretical Analysis

MedKoo Cat#: 597281
Name: Glutaurine
CAS#: 56488-60-9
Chemical Formula: C7H14N2O6S
Exact Mass: 254.06
Molecular Weight: 254.250
Elemental Analysis: C, 33.07; H, 5.55; N, 11.02; O, 37.75; S, 12.61

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Glutaurine; gamma-Glutamyltaurine; Litoralon;

IUPAC/Chemical Name: (2-sulfoethyl)-L-glutamine

InChi Key: LONRGKAJEPECOB-YFKPBYRVSA-N

InChi Code: InChI=1S/C7H14N2O6S/c8-6(10)2-1-5(7(11)12)9-3-4-16(13,14)15/h5,9H,1-4H2,(H2,8,10)(H,11,12)(H,13,14,15)/t5-/m0/s1

SMILES Code: O=C(N)CC[C@@H](C(O)=O)NCCS(=O)(O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 254.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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7: Andiné P, Orwar O, Jacobson I, Sandberg M, Hagberg H. Extracellular acidic sulfur-containing amino acids and gamma-glutamyl peptides in global ischemia: postischemic recovery of neuronal activity is paralleled by a tetrodotoxin-sensitive increase in cysteine sulfinate in the CA1 of the rat hippocampus. J Neurochem. 1991 Jul;57(1):230-6. PubMed PMID: 2051166.

8: Gergely P. Treatment of autoimmune patients. Acta Biomed Ateneo Parmense. 1991;62(3-4):125-30. PubMed PMID: 1840372.

9: Nakamura K, Higashiura K, Nishimura N, Yamamoto A, Tooyama I, Kimura H, Ienaga K. Isolation of glutamyltaurine from bovine brains and proof of its gamma-linkage by the B/E linked scan SIMS technique. J Neurochem. 1990 Sep;55(3):1064-6. PubMed PMID: 2384748.

10: Varga V, Janáky R, Holopainen I, Kontro P, Oja SS. Effect of glutamyltaurine on calcium influx in cultured cerebellar granule cells. Prog Clin Biol Res. 1990;351:141-5. PubMed PMID: 2236122.

11: Horne AL, Simmonds MA. The pharmacology of quisqualate and AMPA in the cerebral cortex of the rat in vitro. Neuropharmacology. 1989 Oct;28(10):1113-8. PubMed PMID: 2682343.

12: Tóth S, Csaba G. gamma-L-glutamyl-taurine (Litoralon) prevents the micronucleus formation induced by mitomycin C. Mutat Res. 1988 Sep-Oct;209(1-2):85-9. PubMed PMID: 3140006.

13: Balázs M, Telegdy G. Effects of glutaurine treatment on electroshock-induced amnesia. Antiamnesic action of glutaurine. Neuropeptides. 1988 Aug-Sep;12(2):55-8. PubMed PMID: 3185869.

14: Schulz H. Spatial working memory in rats: the effect of the dipeptide gamma-L-glutamyl-taurine and haloperidol. Acta Physiol Hung. 1988;72(3-4):263-7. PubMed PMID: 3250206.

15: Marnela KM, Varga V, Dibó G, Lähdesmäki P. Position of the peptide linkage in glutamyl-taurine from calf brain synaptic vesicles. J Neurochem. 1987 Apr;48(4):1090-2. PubMed PMID: 3819721.

16: Baskin S, Bartuska D, Thampi N, McBride M, Finnigan J. The effect of glutaurine on thyroid hormones in the rat. Neuropeptides. 1987 Jan;9(1):45-50. PubMed PMID: 3561723.

17: Toldi J, Fehér O. Interactions of acoustic and somatosensory evoked responses in a polysensory cortex of the cat. Acta Biol Hung. 1987;38(3-4):333-48. PubMed PMID: 3503441.

18: Kovács P, Csaba G, Köhidai L, Török O. Adaptation of the ASTRIN staining technique for quantitative determination of the functional state of the cellular nucleus. Experiments on the nucleoli of CHO cells. Acta Histochem. 1987;81(1):95-8. PubMed PMID: 2436430.

19: Stephens RL Jr, Lee T, Boldry R, Uretsky NJ. Activation of excitatory amino acid receptors may mediate the folate-induced stimulation of locomotor activity after bilateral injection into the rat nucleus accumbens. J Pharmacol Exp Ther. 1986 Dec;239(3):627-33. PubMed PMID: 3025414.

20: Schulz H, Feuer L. Gamma-L-glutamyl-taurine (Litoralon) affects conditioned taste aversion in rats. Acta Physiol Hung. 1986;67(2):233-42. PubMed PMID: 3739747.