WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 555270
Description: SR17018 is an mu-opioid-receptor (MOR) agonist with an EC50 of 97 nM.
MedKoo Cat#: 555270
Chemical Formula: C19H18Cl3N3O
Exact Mass: 409.0515
Molecular Weight: 410.723
Elemental Analysis: C, 55.56; H, 4.42; Cl, 25.89; N, 10.23; O, 3.90
Synonym: SR17018; SR-17018; SR 17018;
IUPAC/Chemical Name: 5,6-dichloro-1-(1-(4-chlorobenzyl)piperidin-4-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one
InChi Key: LAGUDYUGRSQDKS-UHFFFAOYSA-N
InChi Code: InChI=1S/C19H18Cl3N3O/c20-13-3-1-12(2-4-13)11-24-7-5-14(6-8-24)25-18-10-16(22)15(21)9-17(18)23-19(25)26/h1-4,9-10,14H,5-8,11H2,(H,23,26)
SMILES Code: C1=CC(CN2CCC(N3C(=O)NC4C=C(Cl)C(Cl)=CC3=4)CC2)=CC=C1Cl
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 410.723 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
Schmid CL, et al. Bias Factor and Therapeutic Window Correlate to Predict Safer Opioid Analgesics. Cell. 2017 Nov 16;171(5):1165-1175.e13.