MDK-4774 free base
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MedKoo CAT#: 555269

CAS#: 2036044-77-4

Description: MDK-4774, Porcupine-IN-1, is a Porcupine inhibitor. MDK-4774 has CAS#2036044-77-4


Chemical Structure

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MDK-4774 free base
CAS# 2036044-77-4

Theoretical Analysis

MedKoo Cat#: 555269
Name: MDK-4774 free base
CAS#: 2036044-77-4
Chemical Formula: C25H19FN4O
Exact Mass: 410.15
Molecular Weight: 410.452
Elemental Analysis: C, 73.16; H, 4.67; F, 4.63; N, 13.65; O, 3.90

Price and Availability

Size Price Availability Quantity
200mg USD 1650 2 weeks
500mg USD 2250 2 weeks
1g USD 3250 2 weeks
2g USD 5450 2 weeks
Bulk inquiry

Synonym: Porcupine-IN-1; Porcupine-IN 1; Porcupine-IN1; MDK-4774; MDK 4774; MDK4774; Porcn-IN-1

IUPAC/Chemical Name: N-((3-Fluoro-2’-methyl[2,4’-bipyridin]-5-yl)methyl)-9H-carbazole-2-carboxamide

InChi Key: GOMFFTZBKYVUOE-UHFFFAOYSA-N

InChi Code: InChI=1S/C25H19FN4O/c1-15-10-17(8-9-27-15)24-21(26)11-16(13-28-24)14-29-25(31)18-6-7-20-19-4-2-3-5-22(19)30-23(20)12-18/h2-13,30H,14H2,1H3,(H,29,31)

SMILES Code: O=C(C1=CC(NC2=C3C=CC=C2)=C3C=C1)NCC4=CN=C(C5=CC(C)=NC=C5)C(F)=C4

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 410.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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