10-Cl-BBQ
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 563132

CAS#: 23982-76-5

Description: 10-Cl-BBQ is an aryl hydrocarbon receptor (AhR) ligand.


Price and Availability

Size
Price

5mg
USD 265
Size
Price

25mg
USD 800
Size
Price

10-Cl-BBQ, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 563132
Name: 10-Cl-BBQ
CAS#: 23982-76-5
Chemical Formula: C18H9ClN2O
Exact Mass: 304.0403
Molecular Weight: 304.73
Elemental Analysis: C, 70.95; H, 2.98; Cl, 11.63; N, 9.19; O, 5.25


Synonym: 10-Cl-BBQ; 10 Cl BBQ; 10ClBBQ;

IUPAC/Chemical Name: 10-Chloro-7H-benzimidazo[2,1-a]benzo[de]Iso-quinolin-7-one

InChi Key: ZJESJVGSDQOZAT-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H9ClN2O/c19-11-7-8-14-15(9-11)21-17(20-14)12-5-1-3-10-4-2-6-13(16(10)12)18(21)22/h1-9H

SMILES Code: O=C(C1=CC=CC2=CC=CC3=C12)N4C3=NC5=CC=C(Cl)C=C54


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.03.00


References

1: Ehrlich AK, Pennington JM, Wang X, Rohlman D, Punj S, Löhr CV, Newman MT, Kolluri SK, Kerkvliet NI. Activation of the Aryl Hydrocarbon Receptor by 10-Cl-BBQ Prevents Insulitis and Effector T Cell Development Independently of Foxp3+ Regulatory T Cells in Nonobese Diabetic Mice. J Immunol. 2016 Jan 1;196(1):264-73. doi: 10.4049/jimmunol.1501789. Epub 2015 Nov 16. PubMed PMID: 26573835; PubMed Central PMCID: PMC4684970.

2: Punj S, Kopparapu P, Jang HS, Phillips JL, Pennington J, Rohlman D, O'Donnell E, Iversen PL, Kolluri SK, Kerkvliet NI. Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease. PLoS One. 2014 Feb 19;9(2):e88726. doi: 10.1371/journal.pone.0088726. eCollection 2014. PubMed PMID: 24586378; PubMed Central PMCID: PMC3929365.