Veratrole
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MedKoo CAT#: 591767

CAS#: 91-16-7

Description: Veratrole is a building block for the organic synthesis of other aromatic compounds. Veratrole is relatively electron-rich and thus readily undergoes electrophilic substitution.


Chemical Structure

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Veratrole
CAS# 91-16-7

Theoretical Analysis

MedKoo Cat#: 591767
Name: Veratrole
CAS#: 91-16-7
Chemical Formula: C8H10O2
Exact Mass: 138.0681
Molecular Weight: 138.17
Elemental Analysis: C, 69.55; H, 7.30; O, 23.16

Price and Availability

Size Price Availability Quantity
100.0g USD 210.0 2 Weeks
500.0g USD 400.0 2 Weeks
1.0kg USD 470.0 2 Weeks
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Synonym: Veratrole; AI3-02281; AI3 02281; AI302281

IUPAC/Chemical Name: 1,2-Dimethoxybenzene

InChi Key: ABDKAPXRBAPSQN-UHFFFAOYSA-N

InChi Code: InChI=1S/C8H10O2/c1-9-7-5-3-4-6-8(7)10-2/h3-6H,1-2H3

SMILES Code: COC1=CC=CC=C1OC

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 138.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Reconstitution Calculator

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6: Chang MY, Cheng YC. Synthesis of Substituted Tetralins and Benzosuberans via BF3·OEt2-Mediated Formal (4 + 2) and (5 + 2) Stereocontrolled Cycloaddition of 4-Alkenols with Veratrol. Org Lett. 2016 Feb 5;18(3):608-11. doi: 10.1021/acs.orglett.5b03696. Epub 2016 Jan 8. PubMed PMID: 26743459.

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11: Suvitha A, Periandy S, Gayathri P. NBO, HOMO-LUMO, UV, NLO, NMR and vibrational analysis of veratrole using FT-IR, FT-Raman, FT-NMR spectra and HF-DFT computational methods. Spectrochim Acta A Mol Biomol Spectrosc. 2015 Mar 5;138:357-69. doi: 10.1016/j.saa.2014.11.011. Epub 2014 Nov 15. PubMed PMID: 25514662.

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17: Gupta AK, Akhtar TA, Widmer A, Pichersky E, Schiestl FP. Identification of white campion (Silene latifolia) guaiacol O-methyltransferase involved in the biosynthesis of veratrole, a key volatile for pollinator attraction. BMC Plant Biol. 2012 Aug 31;12:158. doi: 10.1186/1471-2229-12-158. PubMed PMID: 22937972; PubMed Central PMCID: PMC3492160.

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20: Breyer S, Effenberger-Neidnicht K, Knauer S, Schobert R. Synthesis, anticancer activity, and iron affinity of the Actinoplanes metabolite 7,8-dihydroxy-1-methylnaphtho[2,3-c]furan-4,9-dione. Bioorg Med Chem. 2011 Feb 1;19(3):1264-7. doi: 10.1016/j.bmc.2010.12.012. Epub 2010 Dec 9. PubMed PMID: 21216607.