BAK2-66

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 563062

CAS#: 1301178-83-5

Description: BAK2-66 is a selective dopamine D3 receptor antagonist.


Price and Availability

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Price

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BAK2-66 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 563062
Name: BAK2-66
CAS#: 1301178-83-5
Chemical Formula: C23H24Cl2FN3O2
Exact Mass: 463.123
Molecular Weight: 464.36
Elemental Analysis: C, 59.49; H, 5.21; Cl, 15.27; F, 4.09; N, 9.05; O, 6.89


Synonym: BAK2-66; BAK2 66; BAK266;

IUPAC/Chemical Name: N-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]-3-fluorobutyl]-2-benzofurancarboxamide

InChi Key: LRBUVURCWWAQQT-UHFFFAOYSA-N

InChi Code: InChI=1S/C23H24Cl2FN3O2/c24-18-5-3-6-19(22(18)25)29-12-10-28(11-13-29)15-17(26)8-9-27-23(30)21-14-16-4-1-2-7-20(16)31-21/h1-7,14,17H,8-13,15H2,(H,27,30)

SMILES Code: O=C(C1=CC2=CC=CC=C2O1)NCCC(F)CN3CCN(C4=CC=CC(Cl)=C4Cl)CC3


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.90.01


References

1: Kumar V, Banala AK, Garcia EG, Cao J, Keck TM, Bonifazi A, Deschamps JR, Newman AH. Chiral Resolution and Serendipitous Fluorination Reaction for the Selective Dopamine D3 Receptor Antagonist BAK2-66. ACS Med Chem Lett. 2014 Mar 24;5(6):647-51. doi: 10.1021/ml500006v. eCollection 2014 Jun 12. PubMed PMID: 24944737; PubMed Central PMCID: PMC4060923.