Lysine HCl
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MedKoo CAT#: 597088

CAS#: 657-27-2 (HCl)

Description: Lysine HCl is an α-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH3+ form under biological conditions), an α-carboxylic acid group (which is in the deprotonated −COO− form under biological conditions), and a side chain lysyl ((CH2)4NH2), classifying it as a basic, charged (at physiological pH), aliphatic amino acid. It is encoded by the codons, AAA and AAG. Like almost all other amino acids, the α-carbon is chiral and lysine may refer to either enantiomer or a racemic mixture of both.


Price and Availability

Size Price Shipping out time Quantity
100g USD 300 2 Weeks
1kg USD 1140 2 Weeks
5kg USD 3950 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-12-05. Prices are subject to change without notice.

Lysine HCl purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 597088
Name: Lysine HCl
CAS#: 657-27-2 (HCl)
Chemical Formula: C6H15ClN2O2
Exact Mass:
Molecular Weight: 182.64
Elemental Analysis: C, 39.46; H, 8.28; Cl, 19.41; N, 15.34; O, 17.52


Synonym: Lysine hydrochloride; L-Lysine monohydrochloride; Lysine HCl; L-Gen; Lyamine;

IUPAC/Chemical Name: L-lysine hydrochloride

InChi Key: BVHLGVCQOALMSV-JEDNCBNOSA-N

InChi Code: InChI=1S/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H/t5-;/m0./s1

SMILES Code: N[C@@H](CCCCN)C(O)=O.[H]Cl


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

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4: Anaya-Reza O, Lopez-Arenas T. Comprehensive assessment of the L-lysine production process from fermentation of sugarcane molasses. Bioprocess Biosyst Eng. 2017 Jul;40(7):1033-1048. doi: 10.1007/s00449-017-1766-2. Epub 2017 Apr 13. PubMed PMID: 28409400.

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7: Vivijs B, Aertsen A, Michiels CW. Identification of Genes Required for Growth of Escherichia coli MG1655 at Moderately Low pH. Front Microbiol. 2016 Oct 25;7:1672. eCollection 2016. PubMed PMID: 27826291; PubMed Central PMCID: PMC5078493.

8: Hochheim J, Kranz A, Krumbach K, Sokolowsky S, Eggeling L, Noack S, Bocola M, Bott M, Marienhagen J. Mutations in MurE, the essential UDP-N-acetylmuramoylalanyl-D-glutamate 2,6-diaminopimelate ligase of Corynebacterium glutamicum: effect on L-lysine formation and analysis of systemic consequences. Biotechnol Lett. 2017 Feb;39(2):283-288. doi: 10.1007/s10529-016-2243-8. Epub 2016 Oct 25. PubMed PMID: 27783176.

9: Hwang HJ, Dornbos P, LaPres JJ. Data on AHR-dependent changes in the mitochondrial proteome in response to ,3,7,8-tetrachlorodibenzo-p-dioxin. Data Brief. 2016 May 20;8:191-5. doi: 10.1016/j.dib.2016.05.023. eCollection 2016 Sep. PubMed PMID: 27331086; PubMed Central PMCID: PMC4898910.

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11: Colina JJ, Miller PS, Lewis AJ, Fischer RL, Diedrichsen RM. Body composition, tissue deposition, and lysine utilization for protein deposition of barrows and gilts fed crystalline or protein-bound lysine. J Anim Sci. 2016 May;94(5):1972-81. doi: 10.2527/jas.2015-0190. PubMed PMID: 27285695.

12: McClelland LJ, Bowler BE. Lower Protein Stability Does Not Necessarily Increase Local Dynamics. Biochemistry. 2016 May 17;55(19):2681-93. doi: 10.1021/acs.biochem.5b01060. Epub 2016 May 4. PubMed PMID: 27104373.

13: Takaoka A, Babar N, Hogan J, Kim M, Price MO, Price FW Jr, Trokel SL, Paik DC. An Evaluation of Lysyl Oxidase-Derived Cross-Linking in Keratoconus by Liquid Chromatography/Mass Spectrometry. Invest Ophthalmol Vis Sci. 2016 Jan 1;57(1):126-36. doi: 10.1167/iovs.15-18105. PubMed PMID: 26780316; PubMed Central PMCID: PMC4727527.

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17: Mehri M, Bagherzadeh Kasmani F, Asghari-Moghadam M. Estimation of lysine requirements of growing Japanese quail during the fourth and fifth weeks of age. Poult Sci. 2015 Aug;94(8):1923-7. doi: 10.3382/ps/pev153. Epub 2015 Jun 11. PubMed PMID: 26069252.

18: Yang Y, Wu Z, Jia S, Dahanayaka S, Feng S, Meininger CJ, McNeal CJ, Wu G. Safety of long-term dietary supplementation with L-arginine in rats. Amino Acids. 2015 Sep;47(9):1909-20. doi: 10.1007/s00726-015-1992-3. Epub 2015 May 7. PubMed PMID: 25948162.

19: Kroeckel S, Dietz C, Schulz C, Susenbeth A. Bioavailability of free lysine and protein-bound lysine from casein and fishmeal in juvenile turbot (Psetta maxima). Br J Nutr. 2015 Mar 14;113(5):718-27. doi: 10.1017/S000711451400381X. Epub 2015 Feb 16. PubMed PMID: 25683818.

20: Hadj Ammar H, Lajili S, Ben Said R, Le Cerf D, Bouraoui A, Majdoub H. Physico-chemical characterization and pharmacological evaluation of sulfated polysaccharides from three species of Mediterranean brown algae of the genus Cystoseira. Daru. 2015 Jan 13;23:1. doi: 10.1186/s40199-015-0089-6. PubMed PMID: 25582169; PubMed Central PMCID: PMC4298055.