Thialysine HCl

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 597022

CAS#: 4099-35-8

Description: Thialysine HCl is utilized in protein synthesis and it is incorporated into proteins in place of lysine.

Chemical Structure

Thialysine HCl
CAS# 4099-35-8

Theoretical Analysis

MedKoo Cat#: 597022
Name: Thialysine HCl
CAS#: 4099-35-8
Chemical Formula: C5H13ClN2O2S
Exact Mass: 0.00
Molecular Weight: 200.680
Elemental Analysis: C, 29.93; H, 6.53; Cl, 17.66; N, 13.96; O, 15.94; S, 15.98

Price and Availability

Size Price Availability Quantity
250mg USD 220
1g USD 390
5g USD 960
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Synonym: Thialysine hydrochloride; LJ 226; NSC 186915; NSC-186915; NSC186915;

IUPAC/Chemical Name: S-(2-aminoethyl)-L-cysteine hydrochloride


InChi Code: InChI=1S/C5H12N2O2S.ClH/c6-1-2-10-3-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H/t4-;/m0./s1


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Product Data:

Preparing Stock Solutions

The following data is based on the product molecular weight 200.680000000000000000000000000000 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Metabolism of triethylenetetramine and 1,12-diamino-3,6,9-triazadodecane by the spermidine/spermine-N(1)-acetyltransferase and thialysine acetyltransferase. Drug Metab Dispos. 2013 Jan;41(1):30-2. doi: 10.1124/dmd.112.047274. Epub 2012 Sep 28. PubMed PMID: 23024204. 14: Marincean S, Rabago Smith M, Beltz L, Borhan B. Selectivity of labeled bromoethylamine for protein alkylation. J Mol Model. 2012 Sep;18(9):4547-56. doi: 10.1007/s00894-012-1461-9. Epub 2012 May 29. PubMed PMID: 22643979. 15: Cerrada-Gimenez M, Weisell J, Hyvönen MT, Park MH, Alhonen L, Vepsäläinen J, Keinänen TA. Complex N-acetylation of triethylenetetramine. Drug Metab Dispos. 2011 Dec;39(12):2242-9. doi: 10.1124/dmd.111.041798. Epub 2011 Aug 30. PubMed PMID: 21878558; PubMed Central PMCID: PMC3226374. 16: Maity AN, Shaikh AC, Srimurugan S, Wu CJ, Chen C, Ke SC. Synthesis of 4-thia-[6-(13)C]lysine from [2- (13)C]glycine: access to site-directed isotopomers of 2-aminoethanol, 2-bromoethylamine and 4-thialysine. 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