S 2160
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 596870

CAS#: 54799-93-8

Description: S 2160 is a synthetic chromogenic substrate for thrombin; liberates p-nitroaniline.


Chemical Structure

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S 2160
CAS# 54799-93-8

Theoretical Analysis

MedKoo Cat#: 596870
Name: S 2160
CAS#: 54799-93-8
Chemical Formula: C33H40N8O6
Exact Mass: 644.3071
Molecular Weight: 644.73
Elemental Analysis: C, 61.48; H, 6.25; N, 17.38; O, 14.89

Price and Availability

Size Price Availability Quantity
5.0mg USD 340.0 2 Weeks
10.0mg USD 570.0 2 Weeks
50.0mg USD 1430.0 2 Weeks
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Synonym: S 2160; S-2160; S2160; Bzphevalargnan; Bz-Phe-val-arg-paranitroanilide;

IUPAC/Chemical Name: N-((S)-1-(((S)-1-(((S)-1-amino-5-guanidino-1-oxopentan-2-yl)(4-nitrophenyl)amino)-3-methyl-1-oxobutan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)benzamide

InChi Key: PIPRQKVYNAHWRU-KCHLEUMXSA-N

InChi Code: InChI=1S/C33H40N8O6/c1-21(2)28(39-31(44)26(20-22-10-5-3-6-11-22)38-30(43)23-12-7-4-8-13-23)32(45)40(24-15-17-25(18-16-24)41(46)47)27(29(34)42)14-9-19-37-33(35)36/h3-8,10-13,15-18,21,26-28H,9,14,19-20H2,1-2H3,(H2,34,42)(H,38,43)(H,39,44)(H4,35,36,37)/t26-,27-,28-/m0/s1

SMILES Code: N=C(N)NCCC[C@@H](C(N)=O)N(C([C@H](C(C)C)NC([C@H](CC1=CC=CC=C1)NC(C2=CC=CC=C2)=O)=O)=O)C3=CC=C([N+]([O-])=O)C=C3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 644.73 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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12: Musci G, Metz GD, Tsunematsu H, Berliner LJ. 4,4'-Bis[8-(phenylamino)naphthalene-1-sulfonate] binding to human thrombins: a sensitive exo site fluorescent affinity probe. Biochemistry. 1985 Apr 9;24(8):2034-9. PubMed PMID: 4016098.

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S 2160

5.0mg / USD 340.0