BW 175

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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 596866

CAS#: 120716-81-6

Description: BW 175 is a bioactive chemical.


Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-08-09. Prices are subject to change without notice.

BW 175 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 596866
Name: BW 175
CAS#: 120716-81-6
Chemical Formula: C37H57N3O7S
Exact Mass: 687.3917
Molecular Weight: 687.93
Elemental Analysis: C, 64.60; H, 8.35; N, 6.11; O, 16.28; S, 4.66


Synonym: BW 175; BW-175; BW175;

IUPAC/Chemical Name: (2S)-N-(1-cyclohexyl-3,4-dihydroxy-5-morpholinopentyl)-2-(3-(ethylsulfonyl)-2-(naphthalen-1-ylmethyl)propanamido)hexanamide

InChi Key: KWZQSSZGRAYHPC-JVYWTFSOSA-N

InChi Code: InChI=1S/C37H57N3O7S/c1-3-5-18-32(38-36(43)30(26-48(45,46)4-2)23-29-16-11-15-27-12-9-10-17-31(27)29)37(44)39-33(28-13-7-6-8-14-28)24-34(41)35(42)25-40-19-21-47-22-20-40/h9-12,15-17,28,30,32-35,41-42H,3-8,13-14,18-26H2,1-2H3,(H,38,43)(H,39,44)/t30?,32-,33?,34?,35?/m0/s1

SMILES Code: OC(C(O)CC(NC([C@H](CCCC)NC(C(CC1=C2C=CC=CC2=CC=C1)CS(=O)(CC)=O)=O)=O)C3CCCCC3)CN4CCOCC4


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Silva GM, Poore MH, Ranches J, Santos GS, Moriel P. Effects of gradual reduction in frequency of energy supplementation on growth and immunity of beef steers. J Anim Sci. 2018 Feb 15;96(1):273-283. doi: 10.1093/jas/skx047. PubMed PMID: 29385600.

2: Capuco AV, Smith JJ, Waldo DR, Rexroad CE Jr. Influence of prepubertal dietary regimen on mammary growth of Holstein heifers. J Dairy Sci. 1995 Dec;78(12):2709-25. PubMed PMID: 8675754.

3: Atsuumi S, Funabashi H, Nakano M, Koike Y, Tanaka S, Harada J, Matsuyama K, Ikenaga T, Morishima H. Renin inhibitors. III. Synthesis and structure-activity relationships of transition-state inhibitors containing dihydroxyethylene isostere at the P1-P1 site. Chem Pharm Bull (Tokyo). 1994 Feb;42(2):306-13. Erratum in: Chem Pharm Bull (Tokyo) 1994 Jun;42(6):1379. PubMed PMID: 8149456.

4: Morishima H, Koike Y, Nakano M, Atsuumi S, Tanaka S, Funabashi H, Hashimoto J, Sawasaki Y, Mino N, Nakano M, et al. A novel nonpeptidic, orally active renin inhibitor. Biochem Biophys Res Commun. 1989 Mar 31;159(3):999-1005. PubMed PMID: 2495004.