Jmv 170

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 596830

CAS#: 117829-60-4

Description: Jmv 170 is the C-terminal heptapeptide of cholecystokinin in which the C-terminal pehnylalanine residue has been replaced by a phenylethylamide group; has partial agonist CCK activity on pancreatic amylase release.

Chemical Structure

Jmv 170
CAS# 117829-60-4

Theoretical Analysis

MedKoo Cat#: 596830
Name: Jmv 170
CAS#: 117829-60-4
Chemical Formula: C51H68N8O14S
Exact Mass: 1048.4576
Molecular Weight: 1049.2
Elemental Analysis: C, 58.38; H, 6.53; N, 10.68; O, 21.35; S, 3.06

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Jmv 170; Jmv-170; Jmv170;

IUPAC/Chemical Name: (6S,9S,15S,18S,21S)-15-((1H-indol-3-yl)methyl)-9,18-dibutyl-21-carbamoyl-2,2-dimethyl-4,7,10,13,16,19-hexaoxo-20-phenethyl-6-(4-(sulfooxy)benzyl)-3-oxa-5,8,11,14,17,20-hexaazatricosan-23-oic acid


InChi Code: InChI=1S/C51H68N8O14S/c1-6-8-18-38(56-47(65)40(58-50(68)72-51(3,4)5)27-33-21-23-35(24-22-33)73-74(69,70)71)46(64)54-31-43(60)55-41(28-34-30-53-37-20-14-13-17-36(34)37)48(66)57-39(19-9-7-2)49(67)59(42(45(52)63)29-44(61)62)26-25-32-15-11-10-12-16-32/h10-17,20-24,30,38-42,53H,6-9,18-19,25-29,31H2,1-5H3,(H2,52,63)(H,54,64)(H,55,60)(H,56,65)(H,57,66)(H,58,68)(H,61,62)(H,69,70,71)/t38-,39-,40-,41-,42-/m0/s1

SMILES Code: O=C(O)C[C@@H](C(N)=O)N(C([C@H](CCCC)NC([C@H](CC1=CNC2=C1C=CC=C2)NC(CNC([C@H](CCCC)NC([C@H](CC3=CC=C(OS(=O)(O)=O)C=C3)NC(OC(C)(C)C)=O)=O)=O)=O)=O)=O)CCC4=CC=CC=C4

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 1049.2 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Nagain C, Lignon MF, Galas MC, Rodriguez M, Martinez J, Rozé C. Large and prolonged in vivo response of pancreatic secretion to phenylethylamide and phenylethylester derivatives of Boc-[Nle28-Nle31]CCK(26-33) in the rat. Peptides. 1992 Nov-Dec;13(6):1127-32. PubMed PMID: 1494494.

2: Gue M, Junien JL, Del Rio C, Bueno L. Neuropeptide Y and sigma ligand (JO 1784) suppress stress-induced colonic motor disturbances in rats through sigma and cholecystokinin receptors. J Pharmacol Exp Ther. 1992 Jun;261(3):850-5. PubMed PMID: 1318376.

3: Botella A, Delvaux M, Berry P, Frexinos J, Bueno L. Cholecystokinin and gastrin induce cell contraction in pig ileum by interacting with different receptor subtypes. Gastroenterology. 1992 Mar;102(3):779-86. PubMed PMID: 1537515.

4: Orosco M, Gourch A, Rodriguez M, Martinez J, Jacquot C, Cohen Y. Comparative activity of two cholecystokinin analogues with partial agonist activity: effects on food intake and brain monoamines. Peptides. 1990 Sep-Oct;11(5):873-7. PubMed PMID: 2284198.