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MedKoo CAT#: 562943

CAS#: 1341167-72-3

Description: VU0410425 is a negative allosteric modulator of metabotropic glutamate receptor subtype 1.

Price and Availability

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Pricing updated 2020-10-29. Prices are subject to change without notice.

VU0410425 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 562943
Name: VU0410425
CAS#: 1341167-72-3
Chemical Formula: C19H16ClN3O3
Exact Mass: 369.088
Molecular Weight: 369.8
Elemental Analysis: C, 61.71; H, 4.36; Cl, 9.59; N, 11.36; O, 12.98

Synonym: VU0410425; VU-0410425; VU 0410425;

IUPAC/Chemical Name: N-[3-Chloro-4-[(1S,5R)-6,6-dimethyl-2,4-dioxo-3-azabicyclo[3.1.0]hexan-3-yl]phenyl]pyridine-2-carboxamide


InChi Code: InChI=1S/C19H16ClN3O3/c1-19(2)14-15(19)18(26)23(17(14)25)13-7-6-10(9-11(13)20)22-16(24)12-5-3-4-8-21-12/h3-9,14-15H,1-2H3,(H,22,24)/t14-,15+

SMILES Code: O=C(C1=NC=CC=C1)NC2=CC=C(N3C([C@]4([H])C(C)(C)[C@]4([H])C3=O)=O)C(Cl)=C2

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Cho HP, Engers DW, Venable DF, Niswender CM, Lindsley CW, Conn PJ, Emmitte KA, Rodriguez AL. A novel class of succinimide-derived negative allosteric modulators of metabotropic glutamate receptor subtype 1 provides insight into a disconnect in activity between the rat and human receptors. ACS Chem Neurosci. 2014 Jul 16;5(7):597-610. doi: 10.1021/cn5000343. Epub 2014 May 15. PubMed PMID: 24798819; PubMed Central PMCID: PMC4102972.