L 741671

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MedKoo CAT#: 596700

CAS#: 187724-85-2

Description: L 741671 is a neurokinin-1 receptor antagonist.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-07-11. Prices are subject to change without notice.

L 741671 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 596700
Name: L 741671
CAS#: 187724-85-2
Chemical Formula: C23H22F6N4O2
Exact Mass: 500.1647
Molecular Weight: 500.44
Elemental Analysis: C, 55.20; H, 4.43; F, 22.78; N, 11.20; O, 6.39

Synonym: L 741671; L-741671; L741671; L-741,671; L 741,671; L741,671;

IUPAC/Chemical Name: 5-(((2R,3R)-3-((3,5-bis(trifluoromethyl)benzyl)oxy)-2-phenylpiperidin-1-yl)methyl)-1,2-dihydro-3H-1,2,4-triazol-3-one


InChi Code: InChI=1S/C23H22F6N4O2/c24-22(25,26)16-9-14(10-17(11-16)23(27,28)29)13-35-18-7-4-8-33(12-19-30-21(34)32-31-19)20(18)15-5-2-1-3-6-15/h1-3,5-6,9-11,18,20H,4,7-8,12-13H2,(H2,30,31,32,34)/t18-,20-/m1/s1

SMILES Code: O=C1NNC(CN2[C@H](C3=CC=CC=C3)[C@H](OCC4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)CCC2)=N1

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Tattersall FD, Rycroft W, Francis B, Pearce D, Merchant K, MacLeod AM, Ladduwahetty T, Keown L, Swain C, Baker R, Cascieri M, Ber E, Metzger J, MacIntyre DE, Hill RG, Hargreaves RJ. Tachykinin NK1 receptor antagonists act centrally to inhibit emesis induced by the chemotherapeutic agent cisplatin in ferrets. Neuropharmacology. 1996;35(8):1121-9. PubMed PMID: 9121615.