L 748780

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MedKoo CAT#: 596692

CAS#: 168086-64-4

Description: L 748780 is a selective inhibitor of inducible COX-2.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-07-11. Prices are subject to change without notice.

L 748780 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 596692
Name: L 748780
CAS#: 168086-64-4
Chemical Formula: C19H14Cl3NO4
Exact Mass: 424.9988
Molecular Weight: 426.67
Elemental Analysis: C, 53.49; H, 3.31; Cl, 24.93; N, 3.28; O, 15.00

Synonym: L 748780; L-748780; L748780; L-748,780; L 748,780; L748,780;

IUPAC/Chemical Name: 2-(5-methoxy-2-methyl-1-(2,4,6-trichlorobenzoyl)-1H-indol-3-yl)acetic acid


InChi Code: InChI=1S/C19H14Cl3NO4/c1-9-12(8-17(24)25)13-7-11(27-2)3-4-16(13)23(9)19(26)18-14(21)5-10(20)6-15(18)22/h3-7H,8H2,1-2H3,(H,24,25)

SMILES Code: O=C(O)CC1=C(C)N(C(C2=C(Cl)C=C(Cl)C=C2Cl)=O)C3=C1C=C(OC)C=C3

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Lau CK, Black WC, Belley M, Chan C, Charleson S, Denis D, Gauthier JY, Gordon R, Guay D, Hamel P, Kargman S, Leblanc Y, Mancini J, Ouellet M, Percival D, Prasit P, Roy P, Skorey K, Tagari P, Vickers P, Wong E. From indomethacin to a selective COX-2 inhibitor. Development of indolalkanoic acids as potent and selective cyclooxygenase-2 inhibitors. Adv Exp Med Biol. 1997;407:73-8. PubMed PMID: 9321934.