L-751788

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 596691

CAS#: 166174-54-5

Description: L-751788 inhibits type 1 5alpha-reductase.


Price and Availability

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L-751788 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 596691
Name: L-751788
CAS#: 166174-54-5
Chemical Formula: C26H36ClNO2
Exact Mass: 429.2435
Molecular Weight: 430.02
Elemental Analysis: C, 72.62; H, 8.44; Cl, 8.24; N, 3.26; O, 7.44


Synonym: L-751788; L 751788; L751788;

IUPAC/Chemical Name: (4aR,4bS,6aR,8S,9aS,9bS,10S,11aR)-8-(4-chlorophenoxy)-1,4a,6a,10-tetramethylhexadecahydro-2H-indeno[5,4-f]quinolin-2-one

InChi Key: UTVZMYJIIKQMGU-DHWOETJDSA-N

InChi Code: InChI=1S/C26H36ClNO2/c1-16-13-22-26(3,12-10-23(29)28(22)4)20-9-11-25(2)15-19(14-21(25)24(16)20)30-18-7-5-17(27)6-8-18/h5-8,16,19-22,24H,9-15H2,1-4H3/t16-,19-,20-,21-,22+,24+,25+,26+/m0/s1

SMILES Code: O=C1N(C)[C@]2([H])C[C@H](C)[C@]([C@]3([H])C[C@H](OC4=CC=C(Cl)C=C4)C[C@@]3(C)CC5)([H])[C@@]5([H])[C@@]2(C)CC1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Constanzer ML, Chavez-Eng CM, Matuszewski BK. Determination of a novel selective inhibitor of type 1 5alpha-reductase in human plasma by liquid chromatography with atmospheric pressure chemical ionization tandem mass spectrometry. J Chromatogr B Biomed Sci Appl. 1998 Aug 25;713(2):371-8. PubMed PMID: 9746252.