L 738872

We are open as normal during COVID-19 pandemic. Order online, same day shipping out.

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 596688

CAS#: 159565-70-5

Description: L 738872 is a bioactive chemical.

Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-07-12. Prices are subject to change without notice.

L 738872 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 596688
Name: L 738872
CAS#: 159565-70-5
Chemical Formula: C34H50ClN5O6S
Exact Mass: 691.317
Molecular Weight: 692.31
Elemental Analysis: C, 58.99; H, 7.28; Cl, 5.12; N, 10.12; O, 13.87; S, 4.63

Synonym: L 738872; L-738872; L738872; L-738,872; L 738,872; L738,872;

IUPAC/Chemical Name: (2R,3R)-2-isopropyl-1,1-dioxidotetrahydrothiophen-3-yl ((2S,3R)-4-((S)-2-(tert-butylcarbamoyl)-4-((2-chloro-6-methylpyridin-4-yl)methyl)piperazin-1-yl)-3-hydroxy-1-phenylbutan-2-yl)carbamate


InChi Code: InChI=1S/C34H50ClN5O6S/c1-22(2)31-29(12-15-47(31,44)45)46-33(43)37-26(17-24-10-8-7-9-11-24)28(41)21-40-14-13-39(19-25-16-23(3)36-30(35)18-25)20-27(40)32(42)38-34(4,5)6/h7-11,16,18,22,26-29,31,41H,12-15,17,19-21H2,1-6H3,(H,37,43)(H,38,42)/t26-,27-,28+,29+,31+/m0/s1

SMILES Code: Cc1nc(Cl)cc(CN2CCN(C[C@@H](O)[C@@H](NC(O[C@@H]3CCS(=O)([C@@H]3C(C)C)=O)=O)Cc4ccccc4)[C@H](C(NC(C)(C)C)=O)C2)c1

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Groenland SL, van Nuland M, Verheijen RB, Schellens JHM, Beijnen JH, Huitema ADR, Steeghs N. Therapeutic Drug Monitoring of Oral Anti-Hormonal Drugs in Oncology. Clin Pharmacokinet. 2018 Jun 4. doi: 10.1007/s40262-018-0683-0. [Epub ahead of print] Review. PubMed PMID: 29862467.

2: J Lu L, Hall L, Liu J. Improving Glaucoma Surgical Outcomes with Adjunct Tools. J Curr Glaucoma Pract. 2018 Jan-Apr;12(1):19-28. doi: 10.5005/jp-journals-10028-1239. Epub 2018 Mar 1. Review. PubMed PMID: 29861578; PubMed Central PMCID: PMC5981089.

3: Junius-Walker U, Onder G, Soleymani D, Wiese B, Albaina O, Bernabei R, Marzetti E; ADVANTAGE JA WP4 group. The essence of frailty: A systematic review and qualitative synthesis on frailty concepts and definitions. Eur J Intern Med. 2018 May 31. pii: S0953-6205(18)30177-8. doi: 10.1016/j.ejim.2018.04.023. [Epub ahead of print] Review. PubMed PMID: 29861330.

4: Li C, Wang P, Zhang L, Li M, Lei X, Liu S, Feng Z, Yao Y, Chang B, Liu B, Shang H. Efficacy and safety of Xuebijing injection (a Chinese patent) for sepsis: a meta-analysis of randomized controlled trials. J Ethnopharmacol. 2018 May 31. pii: S0378-8741(18)30300-3. doi: 10.1016/j.jep.2018.05.043. [Epub ahead of print] Review. PubMed PMID: 29860133.

5: Nardi J, Nascimento S, Göethel G, Gauer B, Sauer E, Fão N, Cestonaro L, Peruzzi C, Souza J, Garcia SC. Inflammatory and oxidative stress parameters as potential early biomarkers for silicosis. Clin Chim Acta. 2018 May 31. pii: S0009-8981(18)30263-8. doi: 10.1016/j.cca.2018.05.045. [Epub ahead of print] Review. PubMed PMID: 29860036.

6: Kampf G. Adaptive microbial response to low level benzalkonium chloride exposure. J Hosp Infect. 2018 May 31. pii: S0195-6701(18)30284-6. doi: 10.1016/j.jhin.2018.05.019. [Epub ahead of print] Review. PubMed PMID: 29859783.

7: Kumar MS, Adki KM. Marine natural products for multi-targeted cancer treatment: A future insight. Biomed Pharmacother. 2018 May 30;105:233-245. doi: 10.1016/j.biopha.2018.05.142. [Epub ahead of print] Review. PubMed PMID: 29859466.

8: Rasheed T, Li C, Bilal M, Yu C, Iqbal HMN. Potentially toxic elements and environmentally-related pollutants recognition using colorimetric and ratiometric fluorescent probes. Sci Total Environ. 2018 May 30;640-641:174-193. doi: 10.1016/j.scitotenv.2018.05.232. [Epub ahead of print] Review. PubMed PMID: 29859435.

9: Poli A, Barbagallo CM, Cicero A, Corsini A, Manzato E, Trimarco B, Bernini F, Visioli F, Bianchi A, Canzone G, Crescini C, de Kreutzenberg S, Ferrara N, Gambacciani M, Ghiselli A, Lubrano C, Marelli G, Marrocco W, Montemurro V, Parretti D, Pedretti R, Perticone F, Stella R, Marangoni F. Nutraceuticals and functional foods for the control of plasma cholesterol levels. An Intersociety position paper. Pharmacol Res. 2018 May 30. pii: S1043-6618(18)30762-X. doi: 10.1016/j.phrs.2018.05.015. [Epub ahead of print] Review. PubMed PMID: 29859248.

10: Kirkland SW, Cross E, Campbell S, Villa-Roel C, Rowe BH. Intramuscular versus oral corticosteroids to reduce relapses following discharge from the emergency department for acute asthma. Cochrane Database Syst Rev. 2018 Jun 2;6:CD012629. doi: 10.1002/14651858.CD012629.pub2. [Epub ahead of print] Review. PubMed PMID: 29859017.

11: Napolitano F, D'Angelo L, de Girolamo P, Avallone L, de Lange P, Usiello A. The Thyroid-target gene Rhes, a novel crossroad for neurological and psychiatric disorders: new insights from animal models. Neuroscience. 2018 May 29. pii: S0306-4522(18)30377-4. doi: 10.1016/j.neuroscience.2018.05.027. [Epub ahead of print] Review. PubMed PMID: 29857029.

12: Eddy CM, Cook JL. Emotions in action: The relationship between motor function and social cognition across multiple clinical populations. Prog Neuropsychopharmacol Biol Psychiatry. 2018 May 29. pii: S0278-5846(18)30211-2. doi: 10.1016/j.pnpbp.2018.05.021. [Epub ahead of print] Review. PubMed PMID: 29857027.

13: Rouanne M, Roumiguié M, Houédé N, Masson-Lecomte A, Colin P, Pignot G, Larré S, Xylinas E, Rouprêt M, Neuzillet Y. Development of immunotherapy in bladder cancer: present and future on targeting PD(L)1 and CTLA-4 pathways. World J Urol. 2018 Jun 1. doi: 10.1007/s00345-018-2332-5. [Epub ahead of print] Review. PubMed PMID: 29855698.

14: Waldner DM, Bech-Hansen NT, Stell WK. Channeling Vision: Ca(V)1.4-A Critical Link in Retinal Signal Transmission. Biomed Res Int. 2018 May 9;2018:7272630. doi: 10.1155/2018/7272630. eCollection 2018. Review. PubMed PMID: 29854783; PubMed Central PMCID: PMC5966690.

15: Le B, Yang SH. Efficacy of Lactobacillus plantarum in prevention of inflammatory bowel disease. Toxicol Rep. 2018 Mar 2;5:314-317. doi: 10.1016/j.toxrep.2018.02.007. eCollection 2018. Review. PubMed PMID: 29854599; PubMed Central PMCID: PMC5977373.

16: Gargiuli C, Schena E, Mattioli E, Columbaro M, D'Apice MR, Novelli G, Greggi T, Lattanzi G. Lamins and bone disorders: current understanding and perspectives. Oncotarget. 2018 Apr 27;9(32):22817-22831. doi: 10.18632/oncotarget.25071. eCollection 2018 Apr 27. Review. PubMed PMID: 29854317; PubMed Central PMCID: PMC5978267.

17: Suntar I, Khan H, Patel S, Celano R, Rastrelli L. An Overview on Citrus aurantium L.: Its Functions as Food Ingredient and Therapeutic Agent. Oxid Med Cell Longev. 2018 May 2;2018:7864269. doi: 10.1155/2018/7864269. eCollection 2018. Review. PubMed PMID: 29854097; PubMed Central PMCID: PMC5954905.

18: Schwen ZR, Gupta M, Pierorazio PM. A Review of Outcomes and Technique for the Robotic-Assisted Laparoscopic Retroperitoneal Lymph Node Dissection for Testicular Cancer. Adv Urol. 2018 May 3;2018:2146080. doi: 10.1155/2018/2146080. eCollection 2018. Review. PubMed PMID: 29853869; PubMed Central PMCID: PMC5960558.

19: Hilmi M, Bartholin L, Neuzillet C. Immune therapies in pancreatic ductal adenocarcinoma: Where are we now? World J Gastroenterol. 2018 May 28;24(20):2137-2151. doi: 10.3748/wjg.v24.i20.2137. Review. PubMed PMID: 29853732; PubMed Central PMCID: PMC5974576.

20: Dalhuisen L. Pyromania in court: Legal insanity versus culpability in Western Europe and the Netherlands (1800-1950). Int J Law Psychiatry. 2018 May - Jun;58:36-47. doi: 10.1016/j.ijlp.2018.02.009. Epub 2018 Mar 9. Review. PubMed PMID: 29853011.