WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 596680
Description: L 731735 is an inhibitor of farnesyltransferase.
MedKoo Cat#: 596680
Name: L 731735
Chemical Formula: C19H40N4O4S
Exact Mass: 420.277
Molecular Weight: 420.61
Elemental Analysis: C, 54.26; H, 9.59; N, 13.32; O, 15.21; S, 7.62
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: L 731735; L-731735; L731735; L-731,735; L 731,735; L731,735;
IUPAC/Chemical Name: (2-((2-amino-3-mercaptopropyl)amino)-3-methylpentyl)-L-alloisoleucyl-L-homoserine
InChi Key: LMTIEVNRUFAFPM-AYMFQPPXSA-N
InChi Code: InChI=1S/C19H40N4O4S/c1-5-12(3)16(21-9-14(20)11-28)10-22-17(13(4)6-2)18(25)23-15(7-8-24)19(26)27/h12-17,21-22,24,28H,5-11,20H2,1-4H3,(H,23,25)(H,26,27)/t12?,13-,14?,15+,16?,17+/m1/s1
SMILES Code: OCC[C@@H](C(O)=O)NC([C@H]([C@H](C)CC)NCC(NCC(N)CS)C(C)CC)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 420.61 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Kohl NE, Mosser SD, deSolms SJ, Giuliani EA, Pompliano DL, Graham SL, Smith RL, Scolnick EM, Oliff A, Gibbs JB. Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor. Science. 1993 Jun 25;260(5116):1934-7. PubMed PMID: 8316833.