L 691678

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MedKoo CAT#: 596658

CAS#: 144210-49-1

Description: L 691678 is a potent inhibitor of leukotriene biosynthesis.

Price and Availability

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Pricing updated 2020-03-29. Prices are subject to change without notice.

L 691678 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 596658
Name: L 691678
CAS#: 144210-49-1
Chemical Formula: C36H30IN5O5S
Exact Mass: 771.1012
Molecular Weight: 771.63
Elemental Analysis: C, 56.04; H, 3.92; I, 16.45; N, 9.08; O, 10.37; S, 4.15

Synonym: L 691678; L-691678; L691678;

IUPAC/Chemical Name: 3-(3-((4-azidophenyl)sulfonyl)-1-(4-iodobenzyl)-5-(quinolin-2-ylmethoxy)-1H-indol-2-yl)-2,2-dimethylpropanoic acid


InChi Code: InChI=1S/C36H30IN5O5S/c1-36(2,35(43)44)20-33-34(48(45,46)29-16-13-26(14-17-29)40-41-38)30-19-28(47-22-27-12-9-24-5-3-4-6-31(24)39-27)15-18-32(30)42(33)21-23-7-10-25(37)11-8-23/h3-19H,20-22H2,1-2H3,(H,43,44)

SMILES Code: O=C(O)C(C)(C)CC(N1CC2=CC=C(I)C=C2)=C(S(=O)(C3=CC=C(N=[N+]=[N-])C=C3)=O)C4=C1C=CC(OCC5=NC6=CC=CC=C6C=C5)=C4

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Vickers PJ, Adam M, Charleson S, Coppolino MG, Evans JF, Mancini JA. Identification of amino acid residues of 5-lipoxygenase-activating protein essential for the binding of leukotriene biosynthesis inhibitors. Mol Pharmacol. 1992 Jul;42(1):94-102. PubMed PMID: 1635556.

2: Mancini JA, Prasit P, Coppolino MG, Charleson P, Leger S, Evans JF, Gillard JW, Vickers PJ. 5-Lipoxygenase-activating protein is the target of a novel hybrid of two classes of leukotriene biosynthesis inhibitors. Mol Pharmacol. 1992 Feb;41(2):267-72. PubMed PMID: 1538707.