L-693612 HCl

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MedKoo CAT#: 596654

CAS#: 138301-72-1

Description: L-693612 HCl is a carbonic anhydrase inhibitor.


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-03-29. Prices are subject to change without notice.

L-693612 HCl is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 596654
Name: L-693612 HCl
CAS#: 138301-72-1
Chemical Formula: C14H25ClN2O5S3
Exact Mass:
Molecular Weight: 432.99
Elemental Analysis: C, 38.84; H, 5.82; Cl, 8.19; N, 6.47; O, 18.47; S, 22.21


Synonym: L-693612 hydrochloride;

IUPAC/Chemical Name: (4S,6S)-6-(3-methoxypropyl)-4-(propylamino)-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide hydrochloride

InChi Key: HRTKKCNBQAABDC-JGAZGGJJSA-N

InChi Code: InChI=1S/C14H24N2O5S3.ClH/c1-3-6-16-12-8-10(5-4-7-21-2)23(17,18)14-11(12)9-13(22-14)24(15,19)20;/h9-10,12,16H,3-8H2,1-2H3,(H2,15,19,20);1H/t10-,12-;/m0./s1

SMILES Code: O=S(C(S1)=CC([C@@H](NCCC)C[C@@H]2CCCOC)=C1S2(=O)=O)(N)=O.Cl


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Wong BK, Bruhin PJ, Lin JH. Dose-dependent pharmacokinetics of L-693,612, a carbonic anhydrase inhibitor, following oral administration in rats. Pharm Res. 1994 Mar;11(3):438-41. PubMed PMID: 8008713.

2: Woolf EJ, Au T, Kasper M, Constanzer M, Matuszewski B. Simultaneous determination of L-693,612, a topical carbonic anhydrase inhibitor, and two potential metabolites in human whole blood by ion-pair high-performance liquid chromatography. J Chromatogr A. 1994 Feb 4;660(1-2):307-12. PubMed PMID: 8148993.