BT2
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MedKoo CAT#: 562929

CAS#: 34576-94-8

Description: BT2 is an allosteric inhibitor of branched-chain alpha-ketoacid dehydrogenase kinase.


Chemical Structure

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BT2
CAS# 34576-94-8

Theoretical Analysis

MedKoo Cat#: 562929
Name: BT2
CAS#: 34576-94-8
Chemical Formula: C9H4Cl2O2S
Exact Mass: 245.93
Molecular Weight: 247.080
Elemental Analysis: C, 43.75; H, 1.63; Cl, 28.69; O, 12.95; S, 12.98

Price and Availability

Size Price Availability Quantity
100mg USD 250 2 Weeks
200mg USD 450 2 Weeks
500mg USD 950 2 Weeks
1g USD 1650 2 Weeks
2g USD 2950 2 Weeks
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Synonym: BT2; BT-2; BT 2;

IUPAC/Chemical Name: 3,6-Dichlorobenzo[b]thiophene-2-carboxylic acid

InChi Key: AAHPIJMQJAZYTM-UHFFFAOYSA-N

InChi Code: InChI=1S/C9H4Cl2O2S/c10-4-1-2-5-6(3-4)14-8(7(5)11)9(12)13/h1-3H,(H,12,13)

SMILES Code: O=C(C1=C(Cl)C2=CC=C(Cl)C=C2S1)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 247.08 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Tso SC, Gui WJ, Wu CY, Chuang JL, Qi X, Skvora KJ, Dork K, Wallace AL, Morlock LK, Lee BH, Hutson SM, Strom SC, Williams NS, Tambar UK, Wynn RM, Chuang DT. Benzothiophene carboxylate derivatives as novel allosteric inhibitors of branched-chain α-ketoacid dehydrogenase kinase. J Biol Chem. 2014 Jul 25;289(30):20583-93. PubMed PMID: 24895126; PubMed Central PMCID: PMC4110271.