L 646462

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MedKoo CAT#: 596584

CAS#: 89149-85-9

Description: L 646462 is an antidopaminergic agent.


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-04-07. Prices are subject to change without notice.

L 646462 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 596584
Name: L 646462
CAS#: 89149-85-9
Chemical Formula: C27H27N3O4
Exact Mass: 457.2002
Molecular Weight: 457.53
Elemental Analysis: C, 70.88; H, 5.95; N, 9.18; O, 13.99


Synonym: L 646462; L-646462; L646462; L-646,462; L 646,462; L646,462;

IUPAC/Chemical Name: (3-methyl-2,5-dioxoimidazolidin-1-yl)methyl 5-(1-methylpiperidin-4-ylidene)-5H-dibenzo[a,d][7]annulene-3-carboxylate

InChi Key: LEHDAQHCDVGZCX-UHFFFAOYSA-N

InChi Code: InChI=1S/C27H27N3O4/c1-28-13-11-20(12-14-28)25-22-6-4-3-5-18(22)7-8-19-9-10-21(15-23(19)25)26(32)34-17-30-24(31)16-29(2)27(30)33/h3-10,15H,11-14,16-17H2,1-2H3

SMILES Code: CN(CC/1)CCC1=C2c3cc(C(OCN4C(CN(C)C4=O)=O)=O)ccc3C=Cc5ccccc/25


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Williams M, Martin GE, Remy DC, Hichens M, Mangel AW, Taylor DA, Yarbrough GG, Bendesky RJ, King SW, Robinson JL, et al. L-646,462, a cyproheptadine-related antagonist of dopamine and serotonin with selectivity for peripheral systems. J Pharmacol Exp Ther. 1984 Jun;229(3):775-81. PubMed PMID: 6547178.