L 366811

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MedKoo CAT#: 596532

CAS#: 127819-95-8

Description: L 366811 is a potent oxytocin antagonist.


Price and Availability

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Pricing updated 2020-03-30. Prices are subject to change without notice.

L 366811 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 596532
Name: L 366811
CAS#: 127819-95-8
Chemical Formula: C43H56N8O6
Exact Mass: 780.4323
Molecular Weight: 780.97
Elemental Analysis: C, 66.13; H, 7.23; N, 14.35; O, 12.29


Synonym: L 366811; L-366811; L366811; L-366,811; L 366,811; L366,811;

IUPAC/Chemical Name: (S)-N-((R)-1-(1H-indol-3-yl)-3-oxopropan-2-yl)-N-(L-isoleucyl)-1-((R)-3-((R)-6-(1,2-dihydropyridine-1-carbonyl)-6-(piperazine-1-carbonyl)cyclohexa-1,3-dien-1-yl)-2-(methylamino)propanoyl)pyrrolidine-2-carboxamide

InChi Key: PQTORSHXODXZHK-FZOIMTHESA-N

InChi Code: 1S/C43H56N8O6/c1-4-29(2)37(44)40(55)51(32(28-52)25-30-27-47-34-15-7-6-14-33(30)34)39(54)36-16-12-22-50(36)38(53)35(45-3)26-31-13-8-9-17-43(31,41(56)48-20-10-5-11-21-48)42(57)49-23-18-46-19-24-49/h5-11,13-15,20,27-29,32,35-37,45-47H,4,12,16-19,21-26,44H2,1-3H3/t29-,32+,35+,36-,37-,43-/m0/s1

SMILES Code: CC[C@@H]([C@H](N)C(N(C([C@@H]1CCCN1C([C@H](NC)CC2=CC=CC[C@]2(C(N3CC=CC=C3)=O)C(N4CCNCC4)=O)=O)=O)[C@@H](C=O)Cc5c6ccccc6[nH]c5)=O)C


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001


References

1: Pettibone DJ, Clineschmidt BV, Lis EV, Ransom RW, Totaro JA, Young GS, Bock MG, Freidinger RM, Veber DF, Williams PD. Bradykinin agonist activity of a novel, potent oxytocin antagonist. Eur J Pharmacol. 1991 Apr 24;196(3):233-7. PubMed PMID: 1893911.