L 363851

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MedKoo CAT#: 596529

CAS#: 111608-31-2

Description: L 363851 is a Neurokinin B agonist.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-05-28. Prices are subject to change without notice.

L 363851 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 596529
Name: L 363851
CAS#: 111608-31-2
Chemical Formula: C38H51N6O7S
Exact Mass: 735.354
Molecular Weight: 735.92
Elemental Analysis: C, 62.02; H, 6.99; N, 11.42; O, 15.22; S, 4.36

Synonym: L 363851; L-363851; L363851; L-363,851; L 363,851; L363,851;

IUPAC/Chemical Name: (2S)-2-((3R)-3-(((S)-3-amino-3,4-dioxo-4-((S)-5-oxopyrrolidin-2-yl)-1-phenyl-3l5-butan-2-yl)phenylalanyl)-2-oxopyrrolidin-1-yl)-N-((S)-1-amino-4-(methylthio)-1-oxobutan-2-yl)-4-methylpentanamide


InChi Code: InChI=1S/C38H51N6O7S/c1-23(2)20-30(36(49)43-28(35(39)48)17-19-52-3)44-18-16-26(37(44)50)33(46)29(21-24-10-6-4-7-11-24)41-31(22-25-12-8-5-9-13-25)38(40,51)34(47)27-14-15-32(45)42-27/h4-13,23,26-31,41H,14-22H2,1-3H3,(H2,39,48)(H2,40,51)(H,42,45)(H,43,49)/t26-,27+,28+,29?,30+,31+/m1/s1

SMILES Code: O=C(N)(C([C@H](CC1)NC1=O)=O)[C@H](CC2=CC=CC=C2)NC(CC3=CC=CC=C3)C([C@@H]4C(N([C@H](C(N[C@H](C(N)=O)CCSC)=O)CC(C)C)CC4)=O)=O

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Grandordy BM, Frossard N, Rhoden KJ, Barnes PJ. Tachykinin-induced phosphoinositide breakdown in airway smooth muscle and epithelium: relationship to contraction. Mol Pharmacol. 1988 May;33(5):515-9. PubMed PMID: 2452969.

2: Stoessl AJ, Dourish CT, Young SC, Williams BJ, Iversen SD, Iversen LL. Senktide, a selective neurokinin B-like agonist, elicits serotonin-mediated behaviour following intracisternal administration in the mouse. Neurosci Lett. 1987 Oct 5;80(3):321-6. PubMed PMID: 2446214.