L 35

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 559185

CAS#: 121809-80-1

Description: L 35 is a negative effector of hemoglobin.


Chemical Structure

img
L 35
CAS# 121809-80-1

Theoretical Analysis

MedKoo Cat#: 559185
Name: L 35
CAS#: 121809-80-1
Chemical Formula: C17H16Cl2N2O4
Exact Mass: 382.0487
Molecular Weight: 383.22
Elemental Analysis: C, 53.28; H, 4.21; Cl, 18.50; N, 7.31; O, 16.70

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: L 35; L-35; L35;

IUPAC/Chemical Name: 2-(4-(1-(3,5-dichlorophenyl)ureido)phenoxy)-2-methylpropanoic acid

InChi Key: DGUVVVAQKVQUFJ-UHFFFAOYSA-N

InChi Code: InChI=1S/C17H16Cl2N2O4/c1-17(2,15(22)23)25-14-5-3-12(4-6-14)21(16(20)24)13-8-10(18)7-11(19)9-13/h3-9H,1-2H3,(H2,20,24)(H,22,23)

SMILES Code: CC(C)(OC1=CC=C(N(C2=CC(Cl)=CC(Cl)=C2)C(N)=O)C=C1)C(O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 383.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Li J, Wu DD, Zhang JX, Wang J, Ma JJ, Hu X, Dong WG. Mitochondrial pathway mediated by reactive oxygen species involvement in α-hederin-induced apoptosis in hepatocellular carcinoma cells. World J Gastroenterol. 2018 May 7;24(17):1901-1910. doi: 10.3748/wjg.v24.i17.1901. PubMed PMID: 29740205; PubMed Central PMCID: PMC5937207.

2: Benkirane H, Taboz Y, Benajiba N, Guennoun Y, Khadmaoui A, Bouziani A, Bajit H, Kari KE, Bentahila N, Barkat A, Aguenaou H. Acceptance of sugar reduction in yoghurt among Moroccan population. Pan Afr Med J. 2017 Dec 15;28:310. doi: 10.11604/pamj.2017.28.310.12257. eCollection 2017. PubMed PMID: 29721140; PubMed Central PMCID: PMC5927571.

3: Xu J, Zhao J, Jia X, Wang G. [Application of early continuous renal replacement therapy in the bundle treatment of severe pneumonia]. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2018 Mar;30(3):246-250. doi: 10.3760/cma.j.issn.2095-4352.2018.03.011. Chinese. PubMed PMID: 29519284.

4: Zhang H, Wang Y, Chen S, Zhao Z, Feng J, Zhang Z, Lu K, Jia J. Water Bacterial and Fungal Community Compositions Associated with Urban Lakes, Xi'an, China. Int J Environ Res Public Health. 2018 Mar 7;15(3). pii: E469. doi: 10.3390/ijerph15030469. PubMed PMID: 29518989; PubMed Central PMCID: PMC5877014.

5: Çetin AÇ, Olgun Y, Özses A, Erdağ TK. A New Trend in the Management of Pediatric Deep Neck Abscess: Achievement of the Medical Treatment Alone. Turk Arch Otorhinolaryngol. 2017 Jun;55(2):57-63. doi: 10.5152/tao.2017.2181. Epub 2017 May 22. PubMed PMID: 29392056; PubMed Central PMCID: PMC5782943.

6: Lommen JM, Flassbeck S, Behl NGR, Niesporek S, Bachert P, Ladd ME, Nagel AM. Probing the microscopic environment of (23) Na ions in brain tissue by MRI: On the accuracy of different sampling schemes for the determination of rapid, biexponential T2* decay at low signal-to-noise ratio. Magn Reson Med. 2018 Aug;80(2):571-584. doi: 10.1002/mrm.27059. Epub 2018 Jan 17. PubMed PMID: 29344985.

7: Chen F, Xu C, Zhang C. [Effect of indwelling nasointestinal tube for enteral nutrition support in patients with severe craniocerebral trauma undergoing mechanical ventilation]. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2018 Jan;30(1):57-60. doi: 10.3760/cma.j.issn.2095-4352.2018.01.011. Chinese. PubMed PMID: 29308759.

8: Samanta S, Poddar B, Azim A, Singh RK, Gurjar M, Baronia AK. Significance of Mini Bronchoalveolar Lavage Fluid Amylase Level in Ventilator-Associated Pneumonia: A Prospective Observational Study. Crit Care Med. 2018 Jan;46(1):71-78. doi: 10.1097/CCM.0000000000002774. PubMed PMID: 29053492.

9: Varbo A, Freiberg JJ, Nordestgaard BG. Remnant Cholesterol and Myocardial Infarction in Normal Weight, Overweight, and Obese Individuals from the Copenhagen General Population Study. Clin Chem. 2018 Jan;64(1):219-230. doi: 10.1373/clinchem.2017.279463. Epub 2017 Oct 11. PubMed PMID: 29021326.

10: Abd-Alla MH, Zohri AA, El-Enany AE, Ali SM. Conversion of food processing wastes to biofuel using clostridia. Anaerobe. 2017 Dec;48:135-143. doi: 10.1016/j.anaerobe.2017.08.011. Epub 2017 Aug 18. PubMed PMID: 28823884.

11: Wilson CR, Pashmakova MB, Heinz JA, Johnson MC, Minard HM, Bishop MA, Barr JW. Biochemical evaluation of storage lesion in canine packed erythrocytes. J Small Anim Pract. 2017 Dec;58(12):678-684. doi: 10.1111/jsap.12713. Epub 2017 Jul 25. PubMed PMID: 28741656.

12: Tripkovic L, Wilson LR, Hart K, Johnsen S, de Lusignan S, Smith CP, Bucca G, Penson S, Chope G, Elliott R, Hyppönen E, Berry JL, Lanham-New SA. Daily supplementation with 15 μg vitamin D(2) compared with vitamin D(3) to increase wintertime 25-hydroxyvitamin D status in healthy South Asian and white European women: a 12-wk randomized, placebo-controlled food-fortification trial. Am J Clin Nutr. 2017 Aug;106(2):481-490. doi: 10.3945/ajcn.116.138693. Epub 2017 Jul 5. PubMed PMID: 28679555.

13: Wu YM, Cao YB, Li XH, Xu LX, Yan B, Li SW, Wang HT, Gao YH, Zhang TT, Zhang YQ, Wang L, Wu XX. [Efficacy and Safety of Posaconazoleon for Primary Antifungal Prophylaxis against Invasive Fungal Disease in Patients with Stem Cell Transplantation]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2017 Jun;25(3):885-889. doi: 10.7534/j.issn.1009-2137.2017.03.045. Chinese. PubMed PMID: 28641654.

14: Fanfani F, Restaino S, Cicogna S, Petrillo M, Montico M, Perrone E, Radillo O, De Leo R, Ceccarello M, Scambia G, Ricci G. Preoperative Serum Human Epididymis Protein 4 Levels in Early Stage Endometrial Cancer: A Prospective Study. Int J Gynecol Cancer. 2017 Jul;27(6):1200-1205. doi: 10.1097/IGC.0000000000001015. PubMed PMID: 28557834.

15: Schade I, Radakovic D, Hoffmann J, Sommer SP, Stefenelli U, Schimmer C, Leyh RG, Aleksic I. Secondary sclerosing cholangitis in cardiac surgical patients: A complication with a dismal prognosis. J Thorac Cardiovasc Surg. 2017 Sep;154(3):906-912. doi: 10.1016/j.jtcvs.2017.04.041. Epub 2017 Apr 27. PubMed PMID: 28554673.

16: Jin M, Wei S, Gao R, Wang K, Xu X, Yao W, Zhang H, Zhou Y, Xu D, Zhou F, Li X. Predictors of Long-Term Mortality in Patients With Acute Heart Failure. Int Heart J. 2017 May 31;58(3):409-415. doi: 10.1536/ihj.16-219. Epub 2017 May 12. PubMed PMID: 28496020.

17: Bikashvili T, Lordkipanidze T, Gogichaishvili N, Pochkhidze N. EFFECT OF ARSENIC EXPOSURE ON BEHAVIOR OF RATS OF VARIOUS AGE GROUPS. Georgian Med News. 2017 Mar;(264):119-126. PubMed PMID: 28480863.

18: Kooijman G, Lopes W, Zhou Z, Guo H, de Kreuk M, Spanjers H, van Lier J. Impact of Coagulant and Flocculant Addition to an Anaerobic Dynamic Membrane Bioreactor (AnDMBR) Treating Waste-Activated Sludge. Membranes (Basel). 2017 Mar 23;7(2). pii: E18. doi: 10.3390/membranes7020018. PubMed PMID: 28333092; PubMed Central PMCID: PMC5489852.

19: Utama DT, Choi JH, Lee CW, Park YS, Lee SK. Effect of mixed hay supplementation during fattening on carcass traits and meat quality of Hanwoo steers. J Anim Sci Technol. 2017 Mar 13;59:6. doi: 10.1186/s40781-017-0131-y. eCollection 2017. PubMed PMID: 28293430; PubMed Central PMCID: PMC5346816.

20: Cai D, He P, Lu X, Zhu C, Zhu J, Zhan Y, Wang Q, Wen Z, Chen S. A novel approach to improve poly-γ-glutamic acid production by NADPH Regeneration in Bacillus licheniformis WX-02. Sci Rep. 2017 Feb 23;7:43404. doi: 10.1038/srep43404. PubMed PMID: 28230096; PubMed Central PMCID: PMC5322528.