L-167307

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 596485

CAS#: 188352-45-6

Description: L-167307 is an inhibitor of p38 kinase.


Price and Availability

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Price

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L-167307 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 596485
Name: L-167307
CAS#: 188352-45-6
Chemical Formula: C22H17FN2OS
Exact Mass: 376.1046
Molecular Weight: 376.44
Elemental Analysis: C, 70.19; H, 4.55; F, 5.05; N, 7.44; O, 4.25; S, 8.52


Synonym: L-167307; L 167307; L167307;

IUPAC/Chemical Name: 4-(2-(4-fluorophenyl)-5-(4-(methylsulfinyl)phenyl)-1H-pyrrol-3-yl)pyridine

InChi Key: IADKHNLYTDEPGD-UHFFFAOYSA-N

InChi Code: InChI=1S/C22H17FN2OS/c1-27(26)19-8-4-16(5-9-19)21-14-20(15-10-12-24-13-11-15)22(25-21)17-2-6-18(23)7-3-17/h2-14,25H,1H3

SMILES Code: O=S(C1=CC=C(C2=CC(C3=CC=NC=C3)=C(C4=CC=C(F)C=C4)N2)C=C1)C


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: de Laszlo SE, Visco D, Agarwal L, Chang L, Chin J, Croft G, Forsyth A, Fletcher D, Frantz B, Hacker C, Hanlon W, Harper C, Kostura M, Li B, Luell S, MacCoss M, Mantlo N, O'Neill EA, Orevillo C, Pang M, Parsons J, Rolando A, Sahly Y, Sidler K, O'Keefe SJ, et al. Pyrroles and other heterocycles as inhibitors of p38 kinase. Bioorg Med Chem Lett. 1998 Oct 6;8(19):2689-94. PubMed PMID: 9873604.