We are open as normal during COVID-19 pandemic. Order online, same day shipping out.

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 596399

CAS#: 150332-35-7

Description: Pamaqueside is an Anti-Atherosclerotic; Hypocholesterolemic.

Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-07-12. Prices are subject to change without notice.

Pamaqueside is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 596399
Name: Pamaqueside
CAS#: 150332-35-7
Chemical Formula: C39H62O14
Exact Mass: 754.414
Molecular Weight: 754.91
Elemental Analysis: C, 62.05; H, 8.28; O, 29.67

Synonym: Pamaqueside; L 165313; L165313; L-165313; CP-148,623; CP 148623; CP-148623; CP148623;

IUPAC/Chemical Name: (4R,5'R,6aS,6bS,8aS,8bR,9S,10R,11aS,12aS,12bS)-4-(((2R,3R,4R,5S,6S)-3,4-dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-5',6a,8a,9-tetramethylicosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-pyran]-7(1H)-one


InChi Code: InChI=1S/C39H62O14/c1-17-7-10-39(48-16-17)18(2)27-24(53-39)12-22-21-6-5-19-11-20(8-9-37(19,3)28(21)23(42)13-38(22,27)4)49-35-33(47)31(45)34(26(15-41)51-35)52-36-32(46)30(44)29(43)25(14-40)50-36/h17-22,24-36,40-41,43-47H,5-16H2,1-4H3/t17-,18+,19?,20-,21+,22+,24+,25-,26+,27+,28-,29-,30+,31-,32-,33-,34-,35-,36+,37+,38+,39-/m1/s1

SMILES Code: O[C@H]([C@H]([C@@H]([C@H](CO)O1)O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)O)[C@@H]1O[C@@H](CC3CC[C@@]4([H])[C@]5([H])C[C@@]6(O[C@@]7(OC[C@H](C)CC7)[C@@H](C)[C@@]6([C@]5(C8)C)[H])[H])CC[C@]3(C)[C@@]4([H])C8=O

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Pamaqueside. CP 148623. Drugs R D. 2002;3(3):175-6. Review. PubMed PMID: 12099162.

2: Dalvie D, O'Donnell J. Metabolism of pamaqueside, a cholesterol absorption inhibitor, in Long-Evans rat: effect of bile duct cannulation on absorption. Xenobiotica. 1999 Oct;29(10):1043-56. PubMed PMID: 10574685.

3: Pamaqueside. CP 148623. Drugs R D. 1999 Jun;1(6):490. PubMed PMID: 10566093.

4: Morehouse LA, Bangerter FW, DeNinno MP, Inskeep PB, McCarthy PA, Pettini JL, Savoy YE, Sugarman ED, Wilkins RW, Wilson TC, Woody HA, Zaccaro LM, Chandler CE. Comparison of synthetic saponin cholesterol absorption inhibitors in rabbits: evidence for a non-stoichiometric, intestinal mechanism of action. J Lipid Res. 1999 Mar;40(3):464-74. PubMed PMID: 10064735.

5: DeNinno MP, McCarthy PA, Duplantier KC, Eller C, Etienne JB, Zawistoski MP, Bangerter FW, Chandler CE, Morehouse LA, Sugarman ED, Wilkins RW, Woody HA, Zaccaro LM. Steroidal glycoside cholesterol absorption inhibitors. J Med Chem. 1997 Aug 1;40(16):2547-54. PubMed PMID: 9258361.

6: Harris WS, Windsor SL, Newton FA, Gelfand RA. Inhibition of cholesterol absorption with CP-148,623 lowers serum cholesterol in humans. Clin Pharmacol Ther. 1997 Mar;61(3):385-9. PubMed PMID: 9084463.

7: McCarthy PA, DeNinno MP, Morehouse LA, Chandler CE, Bangerter FW, Wilson TC, Urban FJ, Walinsky SW, Cosgrove PG, Duplantier K, Etienne JB, Fowler MA, Lambert JF, O'Donnell JP, Pezzullo SL, Watson HA Jr, Wilkins RW, Zaccaro LM, Zawistoski MP. 11-Ketotigogenin cellobioside (pamaqueside): a potent cholesterol absorption inhibitor in the hamster. J Med Chem. 1996 May 10;39(10):1935-7. PubMed PMID: 8642548.