L 158338

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MedKoo CAT#: 596394

CAS#: 133240-38-7

Description: L 158338 is an angiotensin receptor antagonist.

Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-05-29. Prices are subject to change without notice.

L 158338 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 596394
Name: L 158338
CAS#: 133240-38-7
Chemical Formula: C24H25N7
Exact Mass: 411.2171
Molecular Weight: 411.51
Elemental Analysis: C, 70.05; H, 6.12; N, 23.83

Synonym: L 158338; L-158338; L158338;

IUPAC/Chemical Name: 3-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-7-methyl-2-propyl-2,3-dihydro-1H-imidazo[4,5-b]pyridine


InChi Code: InChI=1S/C24H25N7/c1-3-6-21-26-22-16(2)13-14-25-24(22)31(21)15-17-9-11-18(12-10-17)19-7-4-5-8-20(19)23-27-29-30-28-23/h4-5,7-14,21,26H,3,6,15H2,1-2H3,(H,27,28,29,30)


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Owen RA, Molon-Noblot S, Hubert MF, Siegl PK, Eydelloth RS, Keenan KP. Juxtaglomerular cell hypertrophy and hyperplasia induced in rhesus monkeys by angiotensin II receptor antagonists. Lab Invest. 1994 Oct;71(4):543-51. PubMed PMID: 7967510.

2: Werrmann JG, Cohen SM. Comparison of effects of angiotensin-converting enzyme inhibition with those of angiotensin II receptor antagonism on functional and metabolic recovery in postischemic working rat heart as studied by [31P] nuclear magnetic resonance. J Cardiovasc Pharmacol. 1994 Oct;24(4):573-86. PubMed PMID: 7528840.

3: Stearns RA, Miller RR, Arison BH, Rosegay A, Smith JL, Mantlo NB, Chiu SH. Evidence for a 1,2-hydride shift in the microsomal metabolism of the heterocycle L-158,338, a nonpeptide angiotensin II receptor antagonist. Drug Metab Dispos. 1993 Jul-Aug;21(4):670-6. PubMed PMID: 8104127.