L 156903

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 596392

CAS#: 116740-51-3

Description: L 156903 is a bioactive chemica that inhibits the binding of neurotensin to brain tissue.


Price and Availability

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L 156903 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 596392
Name: L 156903
CAS#: 116740-51-3
Chemical Formula: C35H41N7O5S
Exact Mass: 671.289
Molecular Weight: 671.81
Elemental Analysis: C, 62.57; H, 6.15; N, 14.59; O, 11.91; S, 4.77


Synonym: L 156903; L-156903; L156903;

IUPAC/Chemical Name: (3-(10H-phenothiazin-10-yl)propanoyl)-L-arginyl-L-prolyl-L-phenylalanine

InChi Key: BMRQFRNJRZLTND-VBOOUTDYSA-N

InChi Code: InChI=1S/C35H41N7O5S/c36-35(37)38-19-8-12-24(39-31(43)18-21-41-26-13-4-6-16-29(26)48-30-17-7-5-14-27(30)41)33(45)42-20-9-15-28(42)32(44)40-25(34(46)47)22-23-10-2-1-3-11-23/h1-7,10-11,13-14,16-17,24-25,28H,8-9,12,15,18-22H2,(H,39,43)(H,40,44)(H,46,47)(H4,36,37,38)/t24-,25-,28-/m0/s1

SMILES Code: O=C(O)[C@H](CC1=CC=CC=C1)NC([C@H]2N(C([C@H](CCCNC(N)=N)NC(CCN3C4=C(C=CC=C4)SC5=CC=CC=C35)=O)=O)CCC2)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Pettibone DJ, Totaro JA, Harris E, Robinson FM. Heterogeneity of [3H]neurotensin bindings: studies with dynorphin, L-156,903 and levocabastine. Brain Res. 1988 Aug 9;457(2):212-8. PubMed PMID: 2905916.