L 11204

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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 596385

CAS#: 55308-64-0

Description: L 11204 is an Antifertility agent in vivo; inhibitor of prostaglandin synthesis.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-06-02. Prices are subject to change without notice.

L 11204 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 596385
Name: L 11204
CAS#: 55308-64-0
Chemical Formula: C18H17N3O
Exact Mass: 291.1372
Molecular Weight: 291.35
Elemental Analysis: C, 74.20; H, 5.88; N, 14.42; O, 5.49

Synonym: L 11204; L-11204; L11204; DL 204; DL 204IT; DL 204 IT;

IUPAC/Chemical Name: 2-(3-ethoxyphenyl)-5,6-dihydro-[1,2,4]triazolo[5,1-a]isoquinoline


InChi Code: InChI=1S/C18H17N3O/c1-2-22-15-8-5-7-14(12-15)17-19-18-16-9-4-3-6-13(16)10-11-21(18)20-17/h3-9,12H,2,10-11H2,1H3


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Lerner LJ. Development of novel embryotoxic compounds for interceptive fertility control in the dog. J Reprod Fertil Suppl. 1989;39:251-65. PubMed PMID: 2621727.

2: Prasad RS, Vijayan E. A new non-hormonal antifertility drug DL-204: II. Effect on testicular hyaluronidase and gamma-glutamyl transpeptidase in male rats. Contraception. 1987 Nov;36(5):567-80. PubMed PMID: 2896099.

3: Prasad RS, Vijayan E. A new non-hormonal antifertility drug DL-204: I. Effects on testes and accessory glands of reproduction in male rats. Contraception. 1987 Nov;36(5):557-66. PubMed PMID: 2452050.

4: Galliani G, Lerner LJ, Caramel C, Maraschin R, Nani S, Nava A, Nava A. Pregnancy termination in dogs with novel non-hormonal compounds. Studies of 2-(3-ethoxy-phenyl)-5,6-dihydro-s-triazole [5,1-a] isoquinoline (DL 204-IT). Arzneimittelforschung. 1982;32(2):123-7. PubMed PMID: 7199914.

5: Galliani G, Cristina T, Guzzi U, Omodei-Salé A, Assandri A. Increased oral activity of a new class of non-hormonal pregnancy terminating agents. J Pharmacobiodyn. 1982 Jan;5(1):55-61. PubMed PMID: 7077522.

6: Lerner LJ, Oldani C, Vitale A. Inhibition of superovulation and alteration of ova transportation in hamsters by prostaglandin and DL-204-IT, an anti-fertility agent. Prostaglandins Med. 1981 Apr;6(4):369-74. PubMed PMID: 7280116.

7: Assandri A, Perazzi A, Martinelli E, Ferrari P, Ripamonti A, Tuan G, Galliani G. Influence of metabolism on the activity of a new anti-fertility agent, 2-(3-ethoxyphenyl)-5,6-dihydro-s-triazolo [5,1-a]isoquinoline (DL 204-IT), in the rat and the hamster. Arzneimittelforschung. 1981;31(12):2104-11. PubMed PMID: 7199307.

8: Galliani G, Gallico L, Cattaneo C, Assandri A. Pregnancy terminating activity of a new non-hormonal anti-fertility agent, 2-(3-ethoxy-phenyl)-5,6-dihydro-s-triazole [5,1-a] isoquinoline (DL 204-IT) in the rat and the hamster. Studies on the factors affecting its activity. Arzneimittelforschung. 1980;30(6):972-7. PubMed PMID: 7191276.

9: Lerner LJ, Oldani C, Vitale A. Effects of prostaglandin E2 and DL204 IT, an inhibitor of prostaglandin degradation, on ovulation and ovum transport in the hamster. Prostaglandins. 1978 Mar;15(3):525-31. PubMed PMID: 566453.