WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 596372

CAS#: 864445-43-2

Description: JWH 250 is an analytical reference standard categorized as a synthetic cannabinoid. JWH-250 discontinued (DEA controlled substance).

Chemical Structure

CAS# 864445-43-2

Theoretical Analysis

MedKoo Cat#: 596372
Name: JWH-250
CAS#: 864445-43-2
Chemical Formula: C22H25NO2
Exact Mass: 335.1885
Molecular Weight: 335.44
Elemental Analysis: C, 78.77; H, 7.51; N, 4.18; O, 9.54

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: JWH-250; JWH 250; JWH250;

IUPAC/Chemical Name: 2-(2-methoxyphenyl)-1-(1-pentyl-1H-indol-3-yl)ethan-1-one


InChi Code: InChI=1S/C22H25NO2/c1-3-4-9-14-23-16-19(18-11-6-7-12-20(18)23)21(24)15-17-10-5-8-13-22(17)25-2/h5-8,10-13,16H,3-4,9,14-15H2,1-2H3


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 335.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

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9: Ossato A, Canazza I, Trapella C, Vincenzi F, De Luca MA, Rimondo C, Varani K, Borea PA, Serpelloni G, Marti M. Effect of JWH-250, JWH-073 and their interaction on "tetrad", sensorimotor, neurological and neurochemical responses in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2016 Jun 3;67:31-50. doi: 10.1016/j.pnpbp.2016.01.007. Epub 2016 Jan 15. PubMed PMID: 26780169.

10: Cha HJ, Seong YH, Song MJ, Jeong HS, Shin J, Yun J, Han K, Kim YH, Kang H, Kim HS. Neurotoxicity of Synthetic Cannabinoids JWH-081 and JWH-210. Biomol Ther (Seoul). 2015 Nov;23(6):597-603. doi: 10.4062/biomolther.2015.057. Epub 2015 Nov 1. PubMed PMID: 26535086; PubMed Central PMCID: PMC4624077.

11: Borova VL, Gago-Ferrero P, Pistos C, Thomaidis NS. Multi-residue determination of 10 selected new psychoactive substances in wastewater samples by liquid chromatography-tandem mass spectrometry. Talanta. 2015 Nov 1;144:592-603. doi: 10.1016/j.talanta.2015.06.080. Epub 2015 Jul 6. PubMed PMID: 26452866.

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13: Paul BD, Bosy T. A sensitive GC-EIMS method for simultaneous detection and quantification of JWH-018 and JWH-073 carboxylic acid and hydroxy metabolites in urine. J Anal Toxicol. 2015 Apr;39(3):172-82. doi: 10.1093/jat/bku178. Epub 2015 Feb 17. PubMed PMID: 25691387.

14: Gatch MB, Forster MJ. Δ9-Tetrahydrocannabinol-like discriminative stimulus effects of compounds commonly found in K2/Spice. Behav Pharmacol. 2014 Dec;25(8):750-7. doi: 10.1097/FBP.0000000000000093. PubMed PMID: 25325289; PubMed Central PMCID: PMC4216610.

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