JWH-167
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 596370

CAS#: 864445-37-4

Description: JWH 167 is a synthetic cannabinoid (CB) with moderate affinities for both central CB1 (Ki = 90 nM) and peripheral CB2 (Ki = 159 nM) receptors. Its physiological and toxicological properties are not known. This product is intended for forensic and research purposes.

Chemical Structure

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JWH-167
CAS# 864445-37-4
Instruction

Theoretical Analysis

MedKoo Cat#: 596370
Name: JWH-167
CAS#: 864445-37-4
Chemical Formula: C21H23NO
Exact Mass: 305.18
Molecular Weight: 305.420
Elemental Analysis: C, 82.58; H, 7.59; N, 4.59; O, 5.24

Price and Availability

Size Price Availability Quantity
5mg USD 285 2 Weeks
10mg USD 520 2 Weeks
25mg USD 850 2 Weeks
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Synonym: JWH-167; JWH 167; JWH167;

IUPAC/Chemical Name: 1-(1-pentyl-1H-indol-3-yl)-2-phenylethan-1-one

InChi Key: AMCPOEOUXQWESI-UHFFFAOYSA-N

InChi Code: InChI=1S/C21H23NO/c1-2-3-9-14-22-16-19(18-12-7-8-13-20(18)22)21(23)15-17-10-5-4-6-11-17/h4-8,10-13,16H,2-3,9,14-15H2,1H3

SMILES Code: CCCCCN1C=C(C(CC2=CC=CC=C2)=O)C3=C1C=CC=C3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 305.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Pekala K, Michalak A, Kruk-Slomka M, Budzynska B, Biala G. Impacts of cannabinoid receptor ligands on nicotine- and chronic mild stress-induced cognitive and depression-like effects in mice. Behav Brain Res. 2018 Mar 15;347:167-174. doi: 10.1016/j.bbr.2018.03.019. [Epub ahead of print] PubMed PMID: 29551733.

2: de la Asunción-Nadal V, Armenta S, Garrigues S, de la Guardia M. Identification and determination of synthetic cannabinoids in herbal products by dry film attenuated total reflectance-infrared spectroscopy. Talanta. 2017 May 15;167:344-351. doi: 10.1016/j.talanta.2017.02.026. Epub 2017 Feb 12. PubMed PMID: 28340730.

3: Mascini M, Montesano C, Perez G, Wang J, Compagnone D, Sergi M. Selective solid phase extraction of JWH synthetic cannabinoids by using computationally designed peptides. Talanta. 2017 May 15;167:126-133. doi: 10.1016/j.talanta.2017.01.072. Epub 2017 Jan 29. PubMed PMID: 28340702.

4: Funada M. [Pharmacological properties and dependence liabilities of synthetic cannabinoids]. Nihon Arukoru Yakubutsu Igakkai Zasshi. 2010 Jun;45(3):167-74. Review. Japanese. PubMed PMID: 20681249.