WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 596368
CAS#: 824960-02-3
Description: JWH 182 is a potent synthetic cannabinoid (CB), activating the central CB1 receptor with a Ki value of 0.65 nM and the peripheral CB2 receptor with a Ki value of 1.1 nM. Its effects in cells and animals are unknown.
MedKoo Cat#: 596368
Name: JWH-182
CAS#: 824960-02-3
Chemical Formula: C26H27NO
Exact Mass: 369.2093
Molecular Weight: 369.5
Elemental Analysis: C, 84.51; H, 7.37; N, 3.79; O, 4.33
Synonym: JWH-182; JWH 182; JWH182;
IUPAC/Chemical Name: (4-ethylnaphthalen-1-yl)(1-pentyl-1H-indol-3-yl)methanone
InChi Key: LACIUQLUNACUKC-UHFFFAOYSA-N
InChi Code: InChI=1S/C26H27NO/c1-3-5-10-17-27-18-24(22-13-8-9-14-25(22)27)26(28)23-16-15-19(4-2)20-11-6-7-12-21(20)23/h6-9,11-16,18H,3-5,10,17H2,1-2H3
SMILES Code: O=C(C1=C2C=CC=CC2=C(CC)C=C1)C3=CN(CCCCC)C4=C3C=CC=C4
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 369.5 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Hondebrink L, Zwartsen A, Westerink RHS. Effect fingerprinting of new psychoactive substances (NPS): What can we learn from in vitro data? Pharmacol Ther. 2018 Feb;182:193-224. doi: 10.1016/j.pharmthera.2017.10.022. Epub 2017 Oct 31. Review. PubMed PMID: 29097307.
