JTE 7-31

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 596303

CAS#: 194358-72-0

Description: JTE 7-31 is a selective cannabinoid receptor agonist. It is a reasonably highly selective CB2 agonist, but still retains appreciable affinity at CB1, with a Ki of 0.088nM at CB2 vs 11nM at CB1

Chemical Structure

JTE 7-31
CAS# 194358-72-0

Theoretical Analysis

MedKoo Cat#: 596303
Name: JTE 7-31
CAS#: 194358-72-0
Chemical Formula: C22H28N2O3
Exact Mass: 368.21
Molecular Weight: 368.47
Elemental Analysis: C, 71.71; H, 7.66; N, 7.60; O, 13.03

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: JTE 7-31;

IUPAC/Chemical Name: 2-(4-hydroxyphenethyl)-5-methoxy-4-(pentylamino)isoindolin-1-one


InChi Code: InChI=1S/C22H28N2O3/c1-3-4-5-13-23-21-19-15-24(14-12-16-6-8-17(25)9-7-16)22(26)18(19)10-11-20(21)27-2/h6-11,23,25H,3-5,12-15H2,1-2H3


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 368.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Zhou EH, Paolucci M, Dryja TP, Manley T, Xiang C, Rice DS, Prasanna G, Chen A. A Compact Whole-Eye Perfusion System to Evaluate Pharmacologic Responses of Outflow Facility. Invest Ophthalmol Vis Sci. 2017 Jun 1;58(7):2991-3003. doi: 10.1167/iovs.16-20974. PubMed PMID: 28605810.

2: Salort G, Álvaro-Bartolomé M, García-Sevilla JA. Regulation of cannabinoid CB(2) receptor constitutive activity in vivo: repeated treatments with inverse agonists reverse the acute activation of JNK and associated apoptotic signaling in mouse brain. Psychopharmacology (Berl). 2017 Mar;234(6):925-941. doi: 10.1007/s00213-017-4537-5. Epub 2017 Jan 26. PubMed PMID: 28127623.