WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 562809
Description: D011-2120 is an antiviral agent. It acts by blocking microtubule polymerization, disrupting the Golgi complex and inhibiting viral trafficking to the plasma membrane during virus egress.
MedKoo Cat#: 562809
Chemical Formula: C17H15NO3
Exact Mass: 281.1052
Molecular Weight: 281.31
Elemental Analysis: C, 72.58; H, 5.37; N, 4.98; O, 17.06
This product is not in stock, which may be available by custom synthesis.
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Synonym: D011-2120; D011 2120; D0112120;
IUPAC/Chemical Name: 1-[(4-Methoxyphenyl)methyl]-5-methyl-1H-indole-2,3-dione
InChi Key: LVVSKXULWVLTOX-UHFFFAOYSA-N
InChi Code: InChI=1S/C17H15NO3/c1-11-3-8-15-14(9-11)16(19)17(20)18(15)10-12-4-6-13(21-2)7-5-12/h3-9H,10H2,1-2H3
SMILES Code: O=C1N(CC2=CC=C(OC)C=C2)C3=C(C=C(C)C=C3)C1=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 281.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Mudhasani R, Kota KP, Retterer C, Tran JP, Whitehouse CA, Bavari S. High content image-based screening of a protease inhibitor library reveals compounds broadly active against Rift Valley fever virus and other highly pathogenic RNA viruses. PLoS Negl Trop Dis. 2014 Aug 21;8(8):e3095. doi: 10.1371/journal.pntd.0003095. eCollection 2014 Aug. PubMed PMID: 25144302; PubMed Central PMCID: PMC4140764.