Galanthamine
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 596223

CAS#: 357-70-0

Description: Galanthamine is a potent acetylcholinesterase (AChE) inhibitor with IC50 of 500 nM.


Price and Availability

Size
Price

10mg
USD 490
Size
Price

Size
Price

Galanthamine purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 596223
Name: Galanthamine
CAS#: 357-70-0
Chemical Formula: C17H21NO3
Exact Mass: 287.1521
Molecular Weight: 287.35
Elemental Analysis: C, 71.06; H, 7.37; N, 4.87; O, 16.70


Synonym: Galanthamine; HSDB 7361; Reminyl; NSC 100058; NSC100058; NSC-100058; BRN 0093736;

IUPAC/Chemical Name: (4aS,6R,8aS)-3-methoxy-11-methyl-4a,5,9,10,11,12-hexahydro-6H-benzo[2,3]benzofuro[4,3-cd]azepin-6-ol

InChi Key: ASUTZQLVASHGKV-JDFRZJQESA-N

InChi Code: InChI=1S/C17H21NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-6,12,14,19H,7-10H2,1-2H3/t12-,14-,17-/m0/s1

SMILES Code: O[C@H]1C=C[C@@]23CCN(C)CC4=CC=C(OC)C(O[C@@]3([H])C1)=C24


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

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12: Kim SH, Kandiah N, Hsu JL, Suthisisang C, Udommongkol C, Dash A. Beyond symptomatic effects: potential of donepezil as a neuroprotective agent and disease modifier in Alzheimer's disease. Br J Pharmacol. 2017 Dec;174(23):4224-4232. doi: 10.1111/bph.14030. Epub 2017 Oct 29. Review. PubMed PMID: 28901528; PubMed Central PMCID: PMC5715569.

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