Jatropham

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 596171

CAS#: 50656-76-3

Description: Jatropham is a lilium compound.


Chemical Structure

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Jatropham
CAS# 50656-76-3

Theoretical Analysis

MedKoo Cat#: 596171
Name: Jatropham
CAS#: 50656-76-3
Chemical Formula: C5H7NO2
Exact Mass: 113.0477
Molecular Weight: 113.11
Elemental Analysis: C, 53.09; H, 6.24; N, 12.38; O, 28.29

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Jatropham;

IUPAC/Chemical Name: (R)-5-hydroxy-3-methyl-1,5-dihydro-2H-pyrrol-2-one

InChi Key: DORDKUBCRPNETF-SCSAIBSYSA-N

InChi Code: InChI=1S/C5H7NO2/c1-3-2-4(7)6-5(3)8/h2,4,7H,1H3,(H,6,8)/t4-/m1/s1

SMILES Code: O=C1N[C@H](O)C=C1C

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 113.11 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Jovtchev G, Gateva S, Stankov A. Lilium compounds kaempferol and jatropham can modulate cytotoxic and genotoxic effects of radiomimetic zeocin in plants and human lymphocytes In vitro. Environ Toxicol. 2016 Jun;31(6):751-64. doi: 10.1002/tox.22088. Epub 2014 Dec 15. PubMed PMID: 25504804.

2: Thomas R, Sah NK, Sharma PB. Therapeutic biology of Jatropha curcas: a mini review. Curr Pharm Biotechnol. 2008 Aug;9(4):315-24. Review. PubMed PMID: 18691091.

3: Vachálková A, Eisenreichová E, Haladová M, Mucaji P, Józová B, Novotný L. Potential carcinogenic and inhibitory activity of compounds isolated from Lilium candidum L. Neoplasma. 2000;47(5):313-8. PubMed PMID: 11130250.

4: Ori K, Mimaki Y, Mito K, Sashida Y, Nikaido T, Ohmoto T, Masuko A. Jatropham derivatives and steroidal saponins from the bulbs of Lilium hansonii. Phytochemistry. 1992 Aug;31(8):2767-75. PubMed PMID: 1369389.

5: Wiedhopf RM, Trumbull ER, Cole JR. Antitumor agents from Jatropha macrorhiza (Euphorbiaceae) I: isolation and characterization of jatropham. J Pharm Sci. 1973 Jul;62(7):1206-7. PubMed PMID: 4714138.