WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 591134
CAS#: 130-49-4
Description: 2'-Adenylic acid is a bioactive chemical.
MedKoo Cat#: 591134
Name: 2'-Adenylic acid mixed isomers
CAS#: 130-49-4
Chemical Formula: C10H14N5O7P
Exact Mass: 347.0631
Molecular Weight: 347.22
Elemental Analysis: C, 34.59; H, 4.06; N, 20.17; O, 32.25; P, 8.92
Synonym: 2'-Adenylic acid; Adenosine 2′(3′)-monophosphate mixed isomers;
IUPAC/Chemical Name: (2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-3-yl dihydrogen phosphate compound with (2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl dihydrogen phosphate
InChi Key: UQRXDDDXDPEXNS-VQFZJOCSSA-N
InChi Code: InChI=1S/2C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(17)7(4(1-16)21-10)22-23(18,19)20;11-8-5-9(13-2-12-8)15(3-14-5)10-7(22-23(18,19)20)6(17)4(1-16)21-10/h2*2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t2*4-,6-,7-,10-/m11/s1
SMILES Code: OC[C@@H]1[C@@H](O)[C@H]([C@@H](O1)N2C=NC3=C(N)N=CN=C32)OP(O)(O)=O.OC[C@@H]4[C@@H](OP(O)(O)=O)[C@H]([C@@H](O4)N5C=NC6=C(N)N=CN=C65)O
Appearance: Solid powder
Purity: >95% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 347.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Noguchi S. Conformational variation revealed by the crystal structure of RNase U2A complexed with Ca ion and 2'-adenylic acid at 1.03 Å resolution. Protein Pept Lett. 2010 Dec;17(12):1559-61. PubMed PMID: 20858208.
2: Koellner G, Grunert HP, Landt O, Saenger W. Crystal structure of the Tyr45Trp mutant of ribonuclease T1 in a complex with 2'-adenylic acid. Eur J Biochem. 1991 Oct 1;201(1):199-202. PubMed PMID: 1915364.
3: Louie DD, Kaplan NO, McLean JD. Allosteric effect of 2'-adenylic acid on the Pseudomonas pyridine nucleotide transhydrogenase. J Mol Biol. 1972 Oct 14;70(3):651-64. PubMed PMID: 4343310.
